Results 61 to 70 of about 91,638 (253)

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Prevalence and Antibiogram of Methicillin Sensitive and Methicillin Resistant Staphylococcus aureus Isolated from Pus Samples in a Tertiary Care Teaching Hospital

Journal of Pure and Applied Microbiology, 2018
Staphylococcus aureus is an important pathogen causing bacterial infection of skin lesions, such as burns, traumatic lesions, diabetic ulcers and post operative infections.
Sowmya Govindanahalli Shivappa, Raghavendra Rao Morubagal, Rashmi Padmanabha Mahale, Ranjitha Shankare Gowda   +3 more
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Bias in Methicillin Resistance of Staphylococcus aureus

Jundishapur Journal of Microbiology, 2015
Dear Editor Recently, several published papers aiming to isolate and characterize methicillin resistant Staphylococcus aureus (MRSA) have had major bias. For example, an article titled “Microbial Susceptibility and Plasmid Profiles of Methicillin-Resistant Staphylococcus aureus and Methicillin-Susceptible S. aureus” by Shahkarami et al. (1).
openaire   +3 more sources

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Nasal colonization in children with community acquired methicillin-resistant Staphylococcus aureus

Advanced Biomedical Research, 2016
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of infections. The changing epidemiology of MRSA became evident in the 1990s when CA-MRSA cases were first reported.
Fazlollah Davoodabadi, Sina Mobasherizadeh, Kamyar Mostafavizadeh, Hasan Shojaei, Seyed Asghar Havaei, Ali Mehrabi Koushki, Zahra Moghadasizadeh, Mohsen Meidani, Kiana Shirani   +8 more
doaj   +1 more source

Inter‐Verified Binary Classification Models: Unveiling Key Polymer Features Against Staphylococcus aureus

Carbon Innovation, EarlyView.
ABSTRACT Antimicrobial peptides (AMPs) are promising alternatives to antibiotics but require precise and costly sequence control for efficacy. Synthetic polymers composed of acrylate and acrylamide offer a simpler and more time‐efficient antibacterial strategy compared to AMPs.
Jooyoung Roh, Cyrille Boyer, Priyank Kumar   +2 more
wiley   +1 more source

All‐in‐One Intelligent Hemostatic Sponge: Rapid Hemostasis for Non‐Compressive Wounds With Synergetic Enhanced Antibacterial Efficacy and Self‐Reporting Biodegradation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Clinicians often concurrently tackle critical challenges including emergency hemorrhage, secondary infection, and the elusive tracking of biodegradation of conventional hemostatic agents for complex wounds. Here, we report an intelligent hemostatic sponge (spCS@AIE) by incorporating aggregation‐induced emission (AIE) nanoparticles with short‐wave ...
Zhicheng Liu, Yan Zhang, Mengmeng Wang, Ye Li, Heng Sun, Lanqiong Zhang, Xin Bai, Haicheng Wei, Zhi Wang, Hao Guan, Yanzi Xu, Dongfeng Dang, Lingjie Meng   +12 more
wiley   +1 more source

Antibacterial Hydrogel Dressing With Ca2+‐Dependent Hyaluronidase Responsiveness for Accelerating Wound Healing via On‐Demand Release of AIE Photosensitizers

Exploration, EarlyView.
This study innovates a Ca2+‐responsive hydrogel dressing that releases AIE photosensitizers on‐demand. Low Ca2+ enhances bacterial hyaluronidase (HAase) activity, degrading hyaluronic acid dressing to trigger antibacterial ROS release, while high Ca2+ inhibits HAase, preventing overdosing.
Rongwei Cui, Hao Yang, Miaomiao Kang, Zhijun Zhang, Weilin Xu, Yang Jiang, Lizhou Xu, Xiao‐Yong Zhan, Luhan Zhang, Yunsheng Xu, Dong Wang, Ben Zhong Tang, Danyang Li   +12 more
wiley   +1 more source

High-level mupirocin resistance in methicillin-resistant staphylococci isolated from dogs and cats

BMC Veterinary Research, 2019
Background Mupirocin is one of the few antimicrobials active against methicillin-resistant Staphylococcus aureus (MRSA), and is frequently used for the eradication of MRSA nasal colonisation in humans.
Magdalena Kizerwetter-Świda, Dorota Chrobak-Chmiel, Magdalena Rzewuska   +2 more
doaj   +1 more source