Results 71 to 80 of about 91,638 (253)

Safranal epoxide – A potential source for diverse therapeutic applications

open access: yesSaudi Pharmaceutical Journal, 2018
Safranal is an organic compound isolated from saffron oil. Photo epoxidation and thermal reactions of safranal can be a significant tool for the design of drugs to act as anticancer agents and potent chemoprevention.
Suzan Khayyat, Eman Elgendy
doaj   +1 more source

Methicillin-resistant Staphylococcus aureus [PDF]

open access: yesJournal of Cystic Fibrosis, 2013
Turner, Evie   +2 more
openaire   +2 more sources

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam   +2 more
wiley   +1 more source

Prevalence of Vancomycin Resistance in Methicillin-Resistant Staphylococcus Aureus [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2014
Background & Aims: Staphylococcus aureus is one of the most common pathogens in nosocomial infections. Vancomycin is the most important therapeutic drug of choice for treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA ...
Parviz Mohajeri   +4 more
doaj  

Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review

open access: yesJournal of Clinical Ultrasound, EarlyView.
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

open access: yesJournal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang   +3 more
wiley   +1 more source

The impact of a vancomycin intervention on vancomycin‐associated nephrotoxicity in children: a quality improvement initiative

open access: yesJournal of Pharmacy Practice and Research, EarlyView.
Abstract Background Vancomycin is first‐line treatment for methicillin‐resistant Staphylococcus aureus (MRSA) infections. However, despite guideline recommendations, there is no evidence that targeting vancomycin trough concentrations of ≥15 mg/L in children confers clinical benefit and is associated with vancomycin‐associated nephrotoxicity (VAN ...
Megan R. Nettleton   +11 more
wiley   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

open access: yesJournal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira   +3 more
wiley   +1 more source

Staphylococcus aureus and methicillin-resistant Staphylococcus aureus in workers at a university hospital: colonization and beliefs in health.

open access: yesOnline Brazilian Journal of Nursing, 2008
The carrier state of methicillin-resistant Staphylococcus aureus is pointed as infection predictor among hospitalized patients, and factor for environmental and person to person dissemination, including health service workers, when colonized are commonly
Elaine Drehmer de Almeida Cruz   +1 more
doaj   +2 more sources

Detection of Methicillin-Resistant Staphylococcus Aureus by Phenotypical and Molecular Methods among Clinical Isolates

open access: yesMedical Laboratory Journal, 2015
Background and Objective: Increasing prevalence of methicillin resistant Staphylococcus aureus strains (MRSA) with their multidrug resistance potential causes difficulties in the treatment of infections due to these bacteria.
Zare, Z   +3 more
doaj  

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