Results 141 to 150 of about 2,582,173 (296)

Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland [PDF]

, 2015
The study was supported by grants from the UKCRC Translational Infection Research Initiative, and the Medical Research Council Grant Number G1000803) with contributions to the Grant from the Biotechnology and Biological Sciences Research Council, the ...
Holden, MTG, Raven, Kathy E, Feil, EJ, Feil, Edward J, Raven, Kathy E., Donker, Tjibbe, Holden, Matthew T G, Bentley, SD, Estee Torok, M., Reuter, Sandra, Spratt, BG, Aanensen, David M, Török, M Estée, Parkhill, J, Holden, Matthew TG, Reuter, S, Blane, B, Aanensen, David M., Spratt, Brian G, Toeroek, ME, Blane, Beth, Bentley, Stephen D, Grundmann, H, Aanensen, DM, Toeroek, M. Estee, Reynolds, Rosy, Bentley, Stephen D., Török, Estee M, Holden, Matthew T. G., Feil, Edward J., Peacock, Sharon J., Grundmann, Hajo, Reynolds, R, Peacock, SJ, Raven, KE, Spratt, Brian G., Parkhill, Julian, Peacock, Sharon J, Donker, T   +38 more
core   +4 more sources

In Silico Genome-Scale Reconstruction and Validation of the Staphylococcus aureus Metabolic Network [PDF]

, 2005
A genome-scale metabolic model of the Gram-positive, facultative anaerobic opportunistic pathogen Staphylococcus aureus N315 was constructed based on current genomic data, literature, and physiological information.
Panke, Sven, Heinemann, Matthias,, Kümmel, Anne, Ruinatscha, Reto,, Panke, Sven,, Heinemann, Matthias; id_orcid, Kümmel, Anne,, Ruinatscha, Reto, Heinemann, Matthias   +8 more
core   +2 more sources

The Staphylococcus aureus Response to Unsaturated Long Chain Free Fatty Acids: Survival Mechanisms and Virulence Implications. [PDF]

, 2009
Staphylococcus aureus is an important human commensal and opportunistic pathogen responsible for a wide range of infections. Long chain unsaturated free fatty acids represent a barrier to colonisation and infection by S.
Horsburgh Malcolm J., Ward, D, Rees, HH, Ward Deborah, Elisabet Josefsson, Kenny John G., Lindsay Jodi A., John G Kenny, Tarkowski Andrej, Horsburgh, MJ, Hinds Jason, Jonsson Ing-Marie, Ing-Marie Jonsson, Huw H Rees, Deborah Ward, Josefsson Elisabet, Tarkowski, A, Lindsay, JA, Malcolm J Horsburgh, Josefsson, E, Kenny, JG, Hinds, J, Jodi A Lindsay, Rees Huw H., Jason Hinds, Andrej Tarkowski, Jonsson, IM   +26 more
core   +2 more sources

Survival of Staphylococcus aureus ST398 in the human nose after artificial inoculation. [PDF]

, 2012
There is evidence that MRSA ST398 of animal origin is only capable of temporarily occupying the human nose, and it is therefore, often considered a poor human colonizer.We inoculated 16 healthy human volunteers with a mixture of the human MSSA strain ...
Dep Infectieziekten Immunologie, Tavakol, M. (Mehri), Slingerland, B.C.G.C. (Bibi), Vos, M.C. (Margreet), Jodi A. Lindsay, Lindsay, J.A., Tavakol, Mehri, Slingerland, BC, van Wamel, WJ, Lindsay Jodi A., Wagenaar, J.A., Alex van Belkum (38419), Slingerland, B.C.G.C., Jaap A. Wagenaar (103922), Snijders, S.V. (Susan), Henri A. Verbrugh, Mehri Tavakol (106145), Verbrugh Henri A., Tavakol Mehri, Verbrugh, H.A. (Henri), McCarthy, A.J., Snijders, Susan, McCarthy Alex J., Jodi A. Lindsay (119622), Lindsay, JA, Willem J. B. Van Wamel, Vos, Greet, Vos, M.C., Strategic Infection Biology, Susan V Snijders, Jodi A Lindsay, Vos, Greet; id_orcid, Bibi C. G. C. Slingerland (119611), Snijders, SV, Tavakol, M, Verbrugh, H.A., Margreet C Vos, van Wamel, Willem; id_orcid, Jaap A. Wagenaar, Verbrugh, Henri, Snijders, S.V., McCarthy, A.J. (Alex), Wagenaar Jaap A., Advances in Veterinary Medicine, Mehri Tavakol, Slingerland Bibi C. G. C., Verbrugh, HA, Wagenaar, J.A. (Jaap), van Belkum Alex, van Wamel Willem J. B., Alex J. Mccarthy, Susan V. Snijders (106138), Bibi C. G. C. Slingerl, Lindsay, J.A. (Jodi), Henri A Verbrugh, Vos Margreet C., Snijders Susan V., Tavakol, M., Jaap A Wagenaar, Wagenaar, JA, Willem J. B. van Wamel (106154), Margreet C. Vos (119632), Wamel, W.J.B. (Willem) van, van Wamel, W.J., Bibi C G C Slingerland, Susan V. Snijders, Belkum, Alex, van Belkum, A, Mason - Slingerland, Bibi, Willem J B van Wamel, Vos, MC, Belkum, A.F. (Alex) van, McCarthy, AJ, Henri A. Verbrugh (106151), Margreet C. Vos, van Belkum, A., van Wamel, Willem, Alex J McCarthy, Alex van Belkum, Alex J. McCarthy (119618)   +79 more
core   +5 more sources

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

Animal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu, Samantha Howe, Yang Tian, Alisun N. Watson, Jason E. Farrar, Christopher E. Randolph, Jaime Andrés Ángel Isaza, Álvaro José Uribe, Yan Huang, Michael Looper, Jiangchao Zhao, Tsungcheng Tsai   +11 more
wiley   +1 more source

Staphylococcus aureus lipoproteins - TLR2-mediated activation of innate and adaptive immunity [PDF]

, 2010
Staphylococcus (S.) aureus is a very successful pathogen due to its immune evasion strategies. Besides toxins and adhesins, it expresses membrane lipoproteins (Lpp), which are bound by the pattern recognition receptor Toll-like receptor (TLR) 2 in the ...
Schmaler, Mathias
core   +1 more source

A systematic scoping review of metrics utilized to measure antibiotic consumption in hospital settings

British Journal of Clinical Pharmacology, EarlyView.
Abstract Antimicrobial stewardship (AMS) programs were introduced to promote the judicious use of antimicrobials and to combat antimicrobial resistance. Quantifying antibiotic consumption is an important part of AMS initiatives to achieve these objectives.
Marjan Kandimahforoujaki, Kiplin A. Patanwala, Jan‐Willem C. Alffenaar, Asad E. Patanwala   +3 more
wiley   +1 more source

Rapid onset and offset of the interaction between rifampicin and long‐acting cabotegravir/rilpivirine: A pharmacokinetic case report

British Journal of Clinical Pharmacology, EarlyView.
Long‐acting intramuscular cabotegravir/rilpivirine (LA CAB/RPV) is contraindicated with rifampicin because of the risk of markedly reduced antiretroviral exposure, although clinical pharmacokinetic data for this interaction are lacking. We describe a 49‐year‐old man with virologically suppressed HIV‐1 infection receiving LA CAB/RPV every 8 weeks who ...
Emilie M. Gieling, Lisanne A. H. Bevers, Wouter L. Smit, Rosa H. Elias, Annelies Verbon, David M. Burger, Berend J. van Welzen   +6 more
wiley   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source