Clinical performance of the BioFire Blood Culture Identification 2 panel for microorganism species identification and resistance gene detection in blood culture-positive specimens. [PDF]
Naruse H +5 more
europepmc +1 more source
Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino +2 more
wiley +1 more source
Global Research Landscape and Thematic Evolution of Fungi-Derived Antimicrobials Against Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA): A Scientometric Analysis. [PDF]
Ong CJN +9 more
europepmc +1 more source
Fragmentation of the natural product vancoresmycin reveals an essential role of global architecture for biological potency. Vancoresmycin is a structurally complex tetramic‐acid‐containing natural product with potent activity against Gram‐positive bacteria, yet its structure–activity relationships remain poorly defined.
Max Schönenbroicher +8 more
wiley +1 more source
Staphylococcus aureus With Reduced Vancomycin Susceptibility: Diagnostic Challenges in Clinical Settings. [PDF]
Jadhav MB, Karande G, Patil S.
europepmc +1 more source
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite +10 more
wiley +1 more source
Unveiling the bactericidal effects of extracts and phytocompounds from Eichhornia crassipes (Mart.) Solms against methicillin-resistant Staphylococcus aureus (MRSA): An in vitro and in silico approach. [PDF]
Rahman MM +8 more
europepmc +1 more source
Objective Sjögren's disease (SjD) is a chronic autoimmune disease with a complex etiology, where pathogens may influence disease development or progression. Although SjD is not communicable, environmental and endemic pathogen exposures may influence its onset or progression.
Swetha K. Shankar +3 more
wiley +1 more source
Nasal colonization, risk factors, and antibiotic resistance of methicillin-resistant <i>Staphylococcus aureus</i> in Gabonese hospitals. [PDF]
Gondi Nzamba BF +9 more
europepmc +1 more source

