Results 51 to 60 of about 2,461,061 (256)

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF STAPHYLOCOCCUS AUREUS STRAINS IN ISLAMABAD, PAKISTAN

Pakistan Armed Forces Medical Journal, 2021
Objective: To investigate the prevalence of S. aureus in hospitalized patients of Islamabad. Study Design: Cross-sectional study. Study Duration: Pakistan Institute of Medical Science, Applied Microbiology and Biotechnology Lab, COMSATS Institute ...
Yasir Rasheed, Kaleem Imdad, Raheela Yasmin, Ambreen Gul, Aneela Jamil, Ummara Aslam   +5 more
doaj   +1 more source

Clinical and Microbiological Determinants of Outcome in Staphylococcus aureus Bacteraemia. [PDF]

, 2010
Staphylococcus aureus bacteraemia (SAB) is commonly complicated by metastatic infection or relapse after treatment. Objectives. The study aim was to determine the role of bacterial, host, and management factors in development of complicated SAB. Methods.
Karen Walker-Bone, Lindsay, J., Llewelyn, M, Heath, I., Curtis, S., Jodi Lindsay (378699), Lindsay, J, Gillian Baker (16048691), Sally Curtis (11260241), Cubbon, M., Paul, J., John Paul (744142), Llewelyn, M., James Price (6728021), Enright, M.C., Martin Llewelyn (4461757), James Price, Mark C Enright (16048700), Walker-Bone, K., Enright, MC, Curtis, S, Mark C Enright, Martin Llewelyn, Ian Heath, Marc Cubbon, Walker-Bone, K, Price, J., Gillian Baker, Jodi Lindsay, Karen Walker-Bone (2634085), Mark C. Enright, John Paul, Baker, G., Paul, J, Cubbon, M, Sally Curtis, Ian Heath (16048694), Marc Cubbon (16048697), Enright, Mark, Baker, G, Price, J, Heath, I   +41 more
core   +1 more source

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Characterization and Comparison of 2 Distinct Epidemic Community-Associated Methicillin-Resistant Staphylococcus aureus Clones of ST59 Lineage. [PDF]

, 2013
Sequence type (ST) 59 is an epidemic lineage of community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates. Taiwanese CA-MRSA isolates belong to ST59 and can be grouped into 2 distinct clones, a virulent Taiwan clone and a ...
Götz, F, Wolfgang Hoffmann, Yhu-Chering Huang, Clemens Unger (454672), Wolfgang Hoffmann (30039), Huang Yhu-Chering, Unger, C, Chen Chih-Jung, Jodi A. Lindsay (119622), Lindsay, JA, Huang, YC, Clemens Unger, Yhu-Chering Huang (110834), Hoffmann Wolfgang, Jodi A Lindsay, Friedrich Götz (33134), Unger Clemens, Chih-Jung Chen (207116), Chih-Jung Chen, Lindsay Jodi A., Chen, CJ, Hoffmann, W, Götz Friedrich, Friedrich Götz   +23 more
core   +2 more sources

Two‐Dimensional Conjugated Metal Organic Frameworks with Dual Metal Catalytic Active Sites Enhance POD Activity for Antibacterial Treatment

Advanced Science, EarlyView.
A new class of Cu, Ni bimetallic 2D cMOF (CuNi‐HHTP 2D cMOF) featuring dual catalytic sites and high delocalized electronic structure for boosting POD performance. The CuNi‐HHTP 2D‐cMOF enhances the conversion kinetics of H2O2 to ROS, which subsequently enhances antibacterial activity and accelerates the healing of oral ulcers, with macroscopic wound ...
Yixuan Lu, Qinqin Li, Yumin Chen, Shihan Zhang, Shuai Ding, Yanpei Wang, Youxing Liu, Yaru Guo, Xuliang Deng, Shaojun Guo   +9 more
wiley   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Evaluation of spa-typing of methicillin-resistant Staphylococcus aureus using high-resolution melting analysis [PDF]

, 2015
OBJECTIVE: spa-typing of methicillin-resistant Staphylococcus aureus (MRSA) has been widely used in clinical diagnostics and epidemiological studies. We aimed to evaluate high-resolution melting (HRM) as a rapid and cost effective method, to replace DNA ...
Gunnar Sandstrom, Waleed Mazi, Vartul Sangal, Yu, J, Saeed, Amir, Sandstrom, Gunnar, Sangal, Vartul, Sangal, V, Sandstom, Gunnar, Amir Saeed, Mazi, W,, Jun Yu, Sandstrom, G, Saeed, A,, Mazi, Waleed, Yu, Jun   +15 more
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Global distribution and diversity of ovine-associated Staphylococcus aureus [PDF]

, 2014
Staphylococcus aureus is an important pathogen of many species, including sheep, and impacts on both human and animal health, animal welfare, and farm productivity. Here we present the widest global diversity study of ovine-associated S.
Smith, Edward M., Green, Laura E., Green, Laura E.; id_orcid, Manley, Grace, Needs, Polly F.   +4 more
core   +1 more source