Results 141 to 150 of about 299,228 (260)

The Combination of Methionine Adenosyltransferase 2A (MAT2A) Inhibitor AG-270 and Recombinant Methioninase Is Not Cancer-selective in a Co-culture Model of Colon Cancer Cells and Normal Fibroblasts. [PDF]

Cancer Diagn Progn
Kim J, Han Q, Li S, Kang BM, Mizuta K, Asano Y, Miyashi Y, Bouvet M, Hoffman RM.   +8 more
europepmc   +1 more source

Peptidthioester und Peptidtriazolderivate durch Duale Modifikation von Peptidthiosulfonaten auf dem Harz

Angewandte Chemie, EarlyView.
Es wird eine Strategie zur dualen Modifikation von Peptiden auf der Festphase vorgestellt, die die S‐Alkinylierung von Peptidthiosulfonaten und eine regioselektive, iridiumkatalysierte Azid‐Thioalkin‐Zykloaddition umfasst. Dieses Verfahren ermöglicht zuverlässig den Zugang zu Peptiden mit komplexen, nicht‐kanonischen Modifikationen und ist mit ...
Marius Werner, Agnes Bergmann, Chenxi Liu, Mira Behnam, Christian Klein, Franziska Thomas   +5 more
wiley   +1 more source

Potential Treatment for ADHD Based on Recovery from Tryptophan-Induced Central Fatigue by Powerful Competitive Inhibition of L-System Amino Acid Transporter. [PDF]

Int J Tryptophan Res
Yamamoto T, Koleda-Yamamoto B.
europepmc   +1 more source

Methionine [PDF]

, 2020
openaire   +1 more source

Early-life redox perturbation programs intergenerational redox vulnerability through DAF-16/FOXO and SKN-1/Nrf2 signaling in Caenorhabditis elegans. [PDF]

Redox Biol
Liang J, Zhao Y, Xie Y, Li Y, Ma W, Ouyang B, Cao H, Yuan Y, Yue T, Xiao J.   +9 more
europepmc   +1 more source

Biosynthesis of the Fully Saturated C16 Homosesquiterpene Descartane Through Deprotonation With Cyclopropanation

Angewandte Chemie International Edition, EarlyView.
A non‐canonical C16 sesquiterpene synthase from Morganella morganii produces the unusual scaffold descartane. Its cyclisation mechanism was rationalised by isotopic labelling experiments and DFT calculations. Site‐directed mutagenesis altered enzyme function, resulting in alternative products, including voltairene, which requires a different ...
Kexin Yang, Philip Troycke, Bernd Goldfuss, Michael Groll, Jeroen S. Dickschat   +4 more
wiley   +1 more source

Metabolic profile association with white matter hyperintensity in patients with mild cognitive impairment. [PDF]

IBRO Neurosci Rep
Ariaei A, Zamiri R, Ghasemi A, Rezayani B, Rezayani S, Ezatpour A, Farshidi N, Sheikhi EA, Roghanian A, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer's Disease Metabolomics Consortium.   +10 more
europepmc   +1 more source

Dose-Dependent Effects of Selenium Methionine Supplementation on Functional, Structural, and Physiological Characteristics of Rooster Semen During Liquid Storage at 25 °C. [PDF]

Vet Sci
Arif A, Zahoor N, Sadiq A, Sohail T, Tang M, Dong L, Tang J, Khan SZ, Dai G.   +8 more
europepmc   +1 more source

Physiological biodistribution of ¹⁸F-fluciclovine PET in the head: as a baseline for interpretation in patients with suspected glioma. [PDF]

Front Nucl Med
Abe Y, Minamimoto R, Fujita N, Higashi M, Ito R, Kato K, Deguchi S, Ohka F, Saito R, Naganawa S.   +9 more
europepmc   +1 more source

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self‐Sufficient Viral Restriction Factors

Angewandte Chemie International Edition, EarlyView.
CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source