Results 181 to 190 of about 501,506 (307)

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

open access: yesAngewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl   +1 more
wiley   +1 more source

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

open access: yesAngewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran   +11 more
wiley   +1 more source

Response of mid-lactation primiparous Holstein cows to the supplementation of rumen-protected methionine during the summer. [PDF]

open access: yesPLoS One
Monteiro CR   +6 more
europepmc   +1 more source

Ultra-low Concentrations of Cisplatinum Down to the IC<sub>10</sub> in Combination With Recombinant Methioninase Are Synergistically Effective Against Lung Cancer Cells <i>In Vitro</i> and <i>In Vivo</i>. [PDF]

open access: yesIn Vivo
Asano Y   +16 more
europepmc   +1 more source

In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation

open access: yesAngewandte Chemie International Edition, EarlyView.
Chromophore engineering of isoquinoline aldehydes generates TICT‐based fluorogenic dyes for in situ labeling of diverse (bio)molecules with large Stokes shifts compatible with cell imaging. ABSTRACT Simple, efficient transformations of fluorogenic nature that proceed under biocompatible conditions without the formation of byproducts are of high ...
Dongchen Du   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy