Results 211 to 220 of about 291,831 (295)

Reconstitution of Methionine Cycle With ATP Regeneration for Whole-Cell Catalysis of Creatine Production in Engineered Escherichia coli. [PDF]

Microb Biotechnol
Sheng Y, Wu Y, Zhang L, Lv X, Li J, Liu L, Du G, Chen J, Liu Y.   +8 more
europepmc   +1 more source

The Molecular Properties of Honey Bee Acetylcholinesterase Reveal Opportunities to Avoid Off‐Target Effects in Insecticide Discovery

Chemistry – A European Journal, EarlyView.
The structure, dynamics, and kinetics of the essential enzyme acetylcholinesterase (AChE) of honey bee have been studied and compared to AChEs in mosquitoes and mammalians. Profiling of the active sites with selected substrates and AChE inhibitors revealed dramatic differences between the species.
Cecilia Lindgren, Rajeshwari Rajeshwari, Cecilia Springer Engdahl, Rashmi Kumari, Fredrik Ekström, Anna Linusson   +5 more
wiley   +1 more source

Role of Redox-Induced Protein Modifications in Spermatozoa in Health and Disease. [PDF]

Antioxidants (Basel)
Onochie C, Evi K, O'Flaherty C.
europepmc   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

Cytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah, Franz Meitinger, Midori Ohta   +2 more
wiley   +1 more source

Methionine Metabolism Dictates PCSK9 Expression and Antitumor Potency of PD-1 Blockade in MSS Colorectal Cancer. [PDF]

Adv Sci (Weinh)
Wang QL, Chen Z, Lu X, Lin H, Feng H, Weng N, Chen L, Liu M, Long L, Huang L, Deng Y, Zheng K, Zheng X, Li Y, Cai T, Zheng J, Yang W.   +16 more
europepmc   +1 more source

The Relationship of Choline and Cystine to the Methionine Requirement of Young Chickens ,

, 1951
John W. West, C.W. Carrick, S.M. Hauge, E. T. Mertz   +3 more
openalex   +1 more source

Synthesis, Antimycobacterial Activity, and Computational Insight of Novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates against Multidrug‐Resistant Mycobacterium Tuberculosis

ChemMedChem, EarlyView.
A series of 14 novel 1,4‐benzoxazinone derivatives is tested against various strains of Mycobacterium tuberculosis. All compounds show high activity against all tested strains, particularly the resistant strains. Additionally, the novel derivatives exhibit low cytotoxicity toward mammalian Vero cells.
Maria Grazia Mamolo, Emanuele Carosati, Diletta Pasin, Alessandro De Logu, Gianluigi Cabiddu, Marko Jukič, Daniele Zampieri   +6 more
wiley   +1 more source

Impact of Chelation on Reactivity and Cytotoxicity of Hemilabile Biphenyl Gold(III) N‐Heterocyclic Carbene Complexes

ChemMedChem, EarlyView.
An array of eight pairs of biphenyl gold(III) complexes comprising NHC–pyridine ligands having a hemilabile character in vitro displays antiproliferative activity toward human cells in the low micromolar range which is exclusively due to their neutral open form according to speciation studies.
Tom Lacoma, Jérémy Forté, Régina Maruchenko, Romain Morichon, Michèle Salmain, Joëlle Sobczak‐Thépot, Benoît Bertrand   +6 more
wiley   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

ChemPlusChem, EarlyView.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber, Solomon Kojo Attionu, Theodore Kwaku Dayie, Christoph Kreutz   +3 more
wiley   +1 more source

Seo1p, a high-affinity, plasma membrane transporter of the γ-Glu-met dipeptide in yeasts and fungi. [PDF]

J Biol Chem
Dubey P, Ahmad MS, Laxman S, Bachhawat AK.   +3 more
europepmc   +1 more source