Results 121 to 130 of about 18,939,161 (298)
Marc Nelson of the Most Secret Method, Black Cat, Washington, D.C., March 13, 1997
Photograph of Marc Nelson, guitarist for the Washington, D.C. punk band the Most Secret Method, performing at the Black Cat in Washington, D.C. on March 13, 1997.
Baronner, Chris
core
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Flier promoting a concert by the punk bands The Dusters and The Most Secret Method at Go!
core
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The Most Secret Method at the White Lodge, State College, Pennsylvania, March 22, 1998
Photograph of the Washington, D.C. punk band the Most Secret Method performing at the White Lodge in State College, Pennsylvania on March 22, 1998. Band members Johanna Claasen and Ryan Nelson are featured in the photograph, which was taken by musician ...
Baronner, Chris
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The present invention relates, inter alia, to method of assessing the reactivity of a polymerizable material (especially an aluminosilicate) in forming a geopolymer.
Reid, Andrew Wilfred, Zhang, Zuhua
core +1 more source
Method-user-centred method configuration
Method engineering approaches are often based on the assumption that method users are able to explicitly express their situational method requirements. However, similar to software requirements,situational method requirements are often vague and hard to ...
Fredrik Karlsson (7005122) +3 more
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

