Results 121 to 130 of about 320,148 (311)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Weighted Birkhoff Averages and the Parameterization Method

open access: yesSIAM Journal on Applied Dynamical Systems
38 pages, 15 ...
David Blessing, Jason D. Mireles-James
openaire   +2 more sources

Control of Manipulators with Free-Joints via the Averaging Method

open access: yes, 1997
A manipulator with free joints is a class of underactuated mechanisms. Control of such systems is one of major topics in robotics and control engineering.
Takahiro Suzuki   +1 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Determining the Performance of Procurement Methods against Selection Criteria using Outranking - Satisfying Methodology [PDF]

open access: yesJournal of Engineering, Project, and Production Management, 2013
The need to develop a decision support system to determine the most appropriate procurement route for a building project led to the development of various theoretical models. One of the foremost techniques was the multi-attribute utility approach (MAUA).
OJO Stephen Okunlola, IKPO Imeh Johnson
doaj  

Model Averaging Software for Dichotomous Dose Response Risk Estimation

open access: yes
Model averaging has been shown to be a useful method for incorporating model uncertainty in quantitative risk estimation. In certain circumstances this technique is computationally complex, requiring sophisticated software to carry out the computation ...
A. John Bailer, Matthew W. Wheeler
core  

BASED ON AVERAGING METHOD ANALYSIS OF THE SINGLE DEGREE OF FREEDOM AMPLITUDE FREQUENCY

open access: yes, 2019
Improved averaging method was used to receive the vibration differential equation of the approximate solution, and the amplitude frequency response equation was obtained. By employing an averaging method, the transition boundary was calculated. The types
GUO LiFeng   +3 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Initial Conditions, European Colonialism and Africa's Growth [PDF]

open access: yes
We investigate the role of initial conditions at colonial independence on economic growth in Africa in the post-independence period using Bayesian Model Averaging (BMA).
Chris Papageorgiou, Winford H. Masanjala
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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