Results 121 to 130 of about 166,521,371 (311)

An averaging method of particle systems

open access: yes, 2010
A particle system can be described by discrete approach at a microscopic level or continuum approach at a macroscopic level. It is very significant to develop an averaging method to link the two approaches for the development of models allowing a better ...
Yu, Aibing, Zhu, Haiping (R14581)
core  

The method of coordinate averaging

open access: yesJournal of Computational and Applied Mathematics, 1978
AbstractIn this paper a perturbation technique for nearly linear oscillatory systems is developed and a set of second order averaged equations is obtained. The standard form treated is dxdt = F (x, t; ϵ), |ϵ| ⪡ 1, and a well known example is considered in detail so as to show how the asymptotic approximations of other methods can be obtained.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Prioritizing Policies for Pro-Poor Growth: Applying Bayesian Model Averaging to Vietnam [PDF]

open access: yes
Pro-Poor Growth (PPG) is the vision of combining high growth rates with poverty reduction.Due to the myriad of possible determinants of growth and poverty a unique theoretical model for guiding empirical work on PPG is absent, though.Bayesian Model ...
Klump, R., Prüfer, P.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

On the Choice of Prior in Bayesian Model Averaging [PDF]

open access: yes
Bayesian model averaging attempts to combine parameter estimation and model uncertainty in one coherent framework. The choice of prior is then critical.
Kumar, K., Magnus, J.R., Einmahl, J.H.J.
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Bayesian Model Averaging in the Context of Spatial Hedonic Pricing: An Application to Farmland Values [PDF]

open access: yes
Since 1973, British Columbia created an Agricultural Land Reserve to protect farmland from development. In this study, we employ GIS-based hedonic pricing models of farmland values to examine factors that affect farmland prices.
Geerte Cotteleer   +2 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Pre-averaging based estimation of quadratic variation in the presence of noise and jumps : theory, implementation, and empirical evidence [PDF]

open access: yes, 2010
This paper provides theory as well as empirical results for pre-averaging estimators of the daily quadratic variation of asset prices. We derive jump robust inference for pre-averaging estimators, corresponding feasible central limit theorems and an ...
Hautsch, Nikolaus, Podolskij, Mark
core  

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