Results 101 to 110 of about 166,361,988 (297)

Randomised orthogonal matching pursuit algorithm with its application in fast analysis of wide‐angle electromagnetic scattering problems based on compressive sensing

IET Microwaves, Antennas & Propagation
The wide‐angle electromagnetic scattering problems can be rapidly solved by using the method of moments in conjunction with compressive sensing theory. The method mainly has two computational parts: measurement and recovery.
Qi Qi, Yunuo Fan, Xinyuan Cao, Yi Liu, Meng Kong, Zhixiang Huang, Xianliang Wu   +6 more
doaj   +1 more source

Closed-form estimators for the inverse Nakagami distribution

Anais da Academia Brasileira de Ciências
The inverse Nakagami distribution due to Louzada et al. (2018) does not have closed-form maximum likelihood estimators. Closed-form estimators by adapting the method of moments are proposed in this note.
VICTOR NAWA, SARALEES NADARAJAH
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Generalized Methods of Trimmed Moments [PDF]

High breakdown-point regression estimators protect against large errors and data contamination. We adapt and generalize the concept of trimming used by many of these robust estimators so that it can be employed in the context of the generalized method of
Cizek, P.
core  

Free and Open Source Software Codes for Antenna Design: Preliminary Numerical Experiments

Electrical, Control and Communication Engineering, 2019
In both industrial and scientific frameworks, free and open source software codes create novel and interesting opportunities in computational electromagnetics.
Fedeli Alessandro, Montecucco Claudio, Gragnani Gian Luigi   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Democratic Moments

, 2018
This book is available as open access through the Bloomsbury Open Access programme and is available on www.bloomsburycollections.com. This collection of short essays on texts in the history of democracy shows the diversity of ideas that contributed to ...

core   +1 more source