Results 81 to 90 of about 304,989 (278)

Fermat Potentials for Non-Perturbative Gravitational Lensing

, 2002
The images of many distant galaxies are displaced, distorted and often multiplied by the presence of foreground massive galaxies near the line of sight; the foreground galaxies act as gravitational lenses.
Ezra T. Newman, J. Ehlers, S. Capozziello, S. Frittelli, S. Frittelli, Simonetta Frittelli, T. Pyne, T. Pyne, Thomas P. Kling   +8 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Improvement of accuracy of wave-function-matching method for transport calculation

, 2017
The wave-function-matching (WFM) technique for first-principles transport-property calculations was modified by S\o{}rensen {\it et al.} so as to exclude rapidly decreasing evanescent waves [S\o{}rensen {\it et al.}, Phys. Rev. B {\bf 77}, 155301 (2008)].
Blügel, Stefan, Ono, Tomoya, Tsukamoto, Shigeru   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Calibration of optical tweezers with positional detection in the back-focal-plane

, 2006
We explain and demonstrate a new method of force- and position-calibration for optical tweezers with back-focal-plane photo detection. The method combines power spectral measurements of thermal motion and the response to a sinusoidal motion of a ...
Erik Schäffer, Francesco S. Pavone, Frank Jülicher, Happel J., Henrik Flyvbjerg, Jonathon Howard, Landau L. D., Simon F. Tolić-Nørrelykke, Stokes G. G.   +8 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Dynamics of Attention in Depth: Evidence from Mutli-Element Tracking [PDF]

, 1999
The allocation of attention in depth is examined using a multi-element tracking paradigm. Observers are required to track a predefined subset of from two to eight elements in displays containing up to sixteen identical moving elements. We first show that
Mingolla, Ennio, Viswanathan, Lavanya
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Initial Pose Estimation Method for Robust LiDAR-Inertial Calibration and Mapping

Sensors
Handheld LiDAR scanners, which typically consist of a LiDAR sensor, Inertial Measurement Unit, and processor, enable data capture while moving, offering flexibility for various applications, including indoor and outdoor 3D mapping in fields such as ...
Eun-Seok Park , Saba Arshad, Tae-Hyoung Park   +2 more
doaj   +1 more source