Results 81 to 90 of about 174,938,743 (287)
Abstract and Applied Analysis, 2014 We consider system of integral equations related to the weighted Hardy-Littlewood-Sobolev (HLS) inequality in a half space. By the Pohozaev type identity in integral form, we present a Liouville type theorem when the system is in both supercritical and ...
Linfen Cao, Zhaohui Dai
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
MOVING in the Swiss Alps [PDF]
Agriculture has a long tradition in the Grison Alps and plays a major role in forming the typical landscape. Within MOVING, we elaborated the mountain grain value chain and its importance to diversify the region’s traditional animal agriculture with ...
Jaisli, Isabel, Forrer, Carmen
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
A direct method of moving planes for a fully nonlinear nonlocal system
Communications on Pure and Applied Analysis, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Wang, Pengyan, Niu, Pengcheng
openaire +3 more sources
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Structure and motion for dynamic scenes – the case of points moving in planes
, 2002 We consider dynamic scenes consisting of moving points whose motion is constrained to happen in one of a pencil of planes. This is for example the case when rigid objects move independently, but on a common ground plane (each point moves in one of a ...
Sturm, Peter, Peter Sturm
core +1 more source