Results 91 to 100 of about 43,009 (276)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Frontiers in Remote SensingHyperspectral imaging (HSI) captures rich spectral data across hundreds of contiguous bands for diverse applications. Dimension reduction (DR) techniques are commonly used to map the first three reduced dimensions to the red, green, and blue channels for
Vahe Atoyan +5 more
doaj +1 more source
Analyticity and uniform stability of the inverse singular Sturm--Liouville spectral problem [PDF]
, 2011 We prove that the potential of a Sturm--Liouville operator depends analytically and Lipschitz continuously on the spectral data (two spectra or one spectrum and the corresponding norming constants).
Hryniv, Rostyslav O.
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
MathematicsWe propose a low-complexity hybrid beamforming method for massive Multiple-Input Multiple-Output (MIMO) systems that is robust to Channel State Information (CSI) estimation errors. These errors stem from hardware impairments, pilot contamination, limited
S. Pourmohammad Azizi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
FireFires are one of the main sources of disturbance in fire-sensitive ecosystems such as the Amazon. Any attempt to characterize their impacts and establish actions aimed at combating these events presupposes the correct identification of the affected areas.
Poliana Domingos Ferro +8 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Overcoming the Domain Gap Between Multi-Band NIR and RGB for Colorization
IEEE AccessNear-infrared (NIR) imaging has been widely utilized in low-light applications due to its ability to capture fine textures with less noise compared to RGB sensors, but the absence of color information makes NIR imagery less intuitive for human perception.
Gyeong-Eun Youm, Jong-Ok Kim
doaj +1 more source