Results 51 to 60 of about 43,009 (276)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Schrödinger operators with δ and δ′-potentials supported on hypersurfaces [PDF]

, 2012
Self-adjoint Schrödinger operators with δ and δ′-potentials supported on a smooth compact hypersurface are defined explicitly via boundary conditions.
A. Posilicano, B. Simon, B.M. Brown, D. Borisov, D. Colton, F. Gesztesy, F. Gesztesy, F. Gesztesy, G. Grubb, G. Grubb, G. Grubb, G. Grubb, I. Lobanov, J. Behrndt, J. Behrndt, J. Behrndt, J. Herczyński, J. Lions, J. Shabani, J. Shabani, J. Wloka, J.-P. Antoine, J.F. Brasche, Jussi Behrndt, M. Costabel, M. Reed, M. Reed, M.M. Malamud, M.S. Ashbaugh, M.Sh. Birman, M.Sh. Birman, Matthias Langer, P. Deift, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, P. Exner, R.S. Freeman, S. Kondej, T. Kato, T. Kato, V. Ryzhov, V.A. Derkach, V.A. Derkach, V.A. Derkach, V.A. Derkach, V.I. Gorbachuk, Vladimir Lotoreichik, W. McLean, W.O. Amrein   +57 more
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Mapped Chebyshev Pseudo-Spectral Method for Dynamic Aero-Elastic Problem of Limit Cycle Oscillation

International Journal of Aeronautical and Space Sciences, 2018
A mapped Chebyshev pseudo-spectral method is developed as one of the Fourier-spectral approaches and solves nonlinear PDE systems for unsteady flows and dynamic aero-elastic problem in a given time interval, where the flows or elastic motions can be periodic, nonperiodic, or periodic with an unknown frequency.
Dong Kyun Im, Hyun Soon Kim, Seongim Choi   +2 more
openaire   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Numerical solution of scattering problems using a Riemann--Hilbert formulation [PDF]

, 2019
A fast and accurate numerical method for the solution of scalar and matrix Wiener--Hopf problems is presented. The Wiener--Hopf problems are formulated as Riemann--Hilbert problems on the real line, and a numerical approach developed for these problems ...
Luca, Elena, Smith, Stefan G. Llewellyn
core   +2 more sources

Multi-view constrained clustering with an incomplete mapping between views [PDF]

, 2012
Multi-view learning algorithms typically assume a complete bipartite mapping between the different views in order to exchange information during the learning process. However, many applications provide only a partial mapping between the views, creating a
desJardins, Marie, Eaton, Eric, Jacob, Sara   +2 more
core   +1 more source

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Inverse spectral problems for Dirac operators with summable matrix-valued potentials

, 2012
We consider the direct and inverse spectral problems for Dirac operators on $(0,1)$ with matrix-valued potentials whose entries belong to $L_p(0,1)$, $p\in[1,\infty)$.
A. Sakhnovich, A. Sakhnovich, B. Thaller, B.M. Levitan, D. Alpay, D. Chelkak, D. Chelkak, D. V. Puyda, F. Gesztesy, F. Gesztesy, F. Gesztesy, I. Gokhberg, M. Lesch, M.G. Gasymov, M.G. Gasymov, M.M. Malamud, M.M. Malamud, N. Trush, N. Trush, P. Kuchment, R.O. Hryniv, S. Albeverio, S. Clark, V.A. Marchenko, V.A. Sadovnichiy, Ya.V. Mykytyuk, Ya.V. Mykytyuk, Ya.V. Mykytyuk, Ya.V. Mykytyuk   +28 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source