Results 81 to 90 of about 1,449,576 (203)
On the local convergence of the Modified Newton method
The aim of this paper is to investigate the local convergence of the Modified Newton method, i.e. the classical Newton method in which the first derivative is re-evaluated periodically after m steps. The convergence order is shown to be m + 1.
Măruşter Ştefan
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On the generalization of the Complex Step Method
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Abreu, Rafael +2 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
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Two-stage synthesis problems simultaneously consider here-and-now decisions (e.g., optimal investment) and wait-and-see decisions (e.g., optimal operation). The optimal synthesis of energy systems reveals such a two-stage character.
Björn Bahl +3 more
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Background: There is a global increase in demand for hair transplant as well as increasing demand for trained assistants and surgeons. It is a fact that permanent donor hair follicles are limited and any loss during learning is permanent and irreversible,
Anil Kumar Garg, Seema Garg
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Step Size in Stein's Method of Exchangeable Pairs [PDF]
Stein's method of exchangeable pairs is examined through five examples in relation to Poisson and normal distribution approximation. In particular, in the case where the exchangeable pair is constructed from a reversible Markov chain, we analyse how modifying the step size of the chain in a natural way affects the error term in the approximation ...
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We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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The symplecticity of multi-step methods
The paper deals with a Hamiltonian system \[ z'=J\nabla H(z),\;z\in \mathbb{R}^{2n},\;J=\bigl[{0 \atop I} {-I \atop 0}\bigr],\;H:\mathbb{R}^{2n}\to \mathbb{R}^ 1 \tag{1} \] is a Hamiltonian function. (1) is solved by means of the multistep method (2) \(\sum_{k=0}^ m \alpha_ k z_ k=\tau \sum_{k=0}^ m \beta_ k J\nabla H(z_ k)\). This method is symplectic
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