Results 21 to 30 of about 2,532,405 (218)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
BMC NursingBackground Despite the proven benefits of early palliative care, patient communication regarding these services remains elusive. Therefore, this paper aims to (a) provide a focused literature review on nurse palliative care communication addressing ...
Julie B. Grant, Rachel Johnson-Koenke
doaj +1 more source
Interdisciplinary Journal of Partnership StudiesPurpose: This paper reports the findings of a thematic synthesis of 11 case studies, in which two or more individuals or groups work in partnership, purposefully utilising social capital to engage in collective action towards a positive societal and/or ...
Stephen Dare +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effectiveness of Transition Theory-Based Interventions on Outcomes of Nursing Care: A Scoping Review
Iranian Journal of Nursing and Midwifery ResearchBackground: Transition theory addresses the experiences of coping with changes in stages, roles, identities, situations, or positions. It emphasizes understanding the nature of these changes, facilitating and supporting the experience and response at ...
Roya Khorrami Estakhri +6 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Сучасні інформаційні системи, 2019 Providing information superiority over the enemy is becoming a prerequisite for conducting military operations. The main type of information support is military intelligence, and its basis is radio-electronic intelligence.
Ihor Yakhno +4 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Implementation Science Communications, 2021 Background Realist approaches and Normalization Process Theory (NPT) have both gained significant traction in implementation research over the past 10 years.
Sonia Michelle Dalkin +3 more
doaj +1 more source