Results 101 to 110 of about 9,958,067 (302)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Measles – are we dealing with a new epidemy in Poland?

Journal of Education, Health and Sport, 2017
Introduction: In the past few years, a group of parents avoid mandatory vaccination of children has increased. One of the effects of this action is increasing incidence of measles among unvaccinated people.
Maciej Rutkowski, Łukasz Świerszcz, Anna Roszkowska, Anna Taracha, Halina Piecewicz-Szczęsna   +4 more
doaj   +1 more source

Malthus and Ricardo on Economic Methodology [PDF]

, 1996
The paper is a comparative study of the methodologies of Malthus and Ricardo. Its claims are: (i) economic laws almost always admit of exceptions for Malthus; for Ricardo even contingent predictions allow no exception apart from random temporary ...
Cremaschi, Sergio Volodia Marcello, Dascal, Marcelo   +1 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Selected Reliable Indicators of Sustainable Land Management (SLM) in the European Union

Visegrad Journal on Bioeconomy and Sustainable Development, 2017
The concept of sustainability and the feasibility options have been discussed in specialized literature sources for about three decades only. Sustainable development has several definitions; it is defined both in narrow and wider sense. The definition of
Tóth-Naár Zsuzsanna, Naár Tamás Antal, Sőreg Ádám Pál, Vinogradov Sergey   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Drug re-purposing to improve outcomes in the management of prostate cancer – aims, outcome measures and design of current phase III trials

BMC Pharmacology and Toxicology
Prostate cancer remains a major cause of cancer morbidity and mortality and is rising in incidence across the world. Although a succession of randomised controlled trials have improved outcomes across all stages of disease, there remain significant ...
Duncan C. Gilbert, Ruth E. Langley, Dami Ayadi, Mannab Berhanu, Lakshmi Kowdley Hemanth, Seunghee Kwon, Hossameldin Abdallah, Angela Meade, Noel Clarke, Silke Gillessen, Nicholas James, Gauthier Bouche, Mahesh Parmar, Matthew Nankivell, Laura Murphy   +14 more
doaj   +1 more source

Methodology for quantum logic gate constructions

, 2000
We present a general method to construct fault-tolerant quantum logic gates with a simple primitive, which is an analog of quantum teleportation. The technique extends previous results based on traditional quantum teleportation (Gottesman and Chuang ...
A. Kitaev, A. M. Steane, A. R. Calderbank, A. Steane, C. H. Bennett, D. Gottesman, D. Gottesman, D. Gottesman, Debbie W. Leung, E. Knill, G. Brassard, Isaac L. Chuang, J. L. Hennessey, J. Preskill, M. A. Nielsen, P. O. Boykin, P. Shor, P. Shor, R. Cleve, Xinlan Zhou   +19 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source