Results 91 to 100 of about 9,808,147 (301)
Measles – are we dealing with a new epidemy in Poland?
Journal of Education, Health and Sport, 2017 Introduction: In the past few years, a group of parents avoid mandatory vaccination of children has increased. One of the effects of this action is increasing incidence of measles among unvaccinated people.
Maciej Rutkowski +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Selected Reliable Indicators of Sustainable Land Management (SLM) in the European Union
Visegrad Journal on Bioeconomy and Sustainable Development, 2017 The concept of sustainability and the feasibility options have been discussed in specialized literature sources for about three decades only. Sustainable development has several definitions; it is defined both in narrow and wider sense. The definition of
Tóth-Naár Zsuzsanna +3 more
doaj +1 more source
Application of Advanced Stated Preference Design Methodology [PDF]
, 1997 This paper demonstrates the application of the design methodology developed in the Advanced Stated Preference Design project to stated preference experiments. The paper considers binary response experimental designs of two, three and four variables.
Clark, S.D., Toner, J.P.
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Assessing Questionable and Responsible Research Practices in Psychology Master’s Theses
Behavioral SciencesRecent research has documented both questionable and responsible research practices in published psychology research, but it is unclear which research practices psychology students engage in when graduating from their master’s program.
Hilde E. M. Augusteijn +3 more
doaj +1 more source