Results 71 to 80 of about 9,397,880 (350)

The prevalence of alcohol use among medical students in Poland

open access: yesJournal of Education, Health and Sport, 2017
Introduction. Alcohol is the most widely used drug worldwide. Medical students should be aware of its possible harmful properties although they are known to consume large amounts of alcohol.
Mateuz Woźniakowski   +5 more
doaj   +3 more sources

Methodology of ergronomics

open access: yesThe Japanese journal of ergonomics, 1966
Explanatory remarks on study methods for human work motion are described. In this article the therblig method and the use of a simo chart are introduced.
openaire   +4 more sources

Evaluating Lifeworld as an emancipatory methodology [PDF]

open access: yes, 2007
Disability research is conducted within a highly politicised ‘hotbed’ of competing paradigms and principles. New researchers, who want to work within the social model, are soon faced with complex and challenging methodological and philosophical dilemmas.
Ashworth P.D.   +31 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Methodology questioned

open access: yesAustralian Journal of Physiotherapy, 2000
I read with interest the article by Kay S, Haensel N and Stiller K (2000): The effect of passive mobilisation following fractures involving the distal radius: A randomised study. Australian Journal of Physiotherapy 46: 93–101. Of concern to me are several aspects of the methodology of this research. In my opinion, the sample of 40 does not appear to be
openaire   +2 more sources

Research methodology in montanistic tourism [PDF]

open access: yes, 2017
Research methodology in montanistic tourism involves the archival research and study of special literature, surface and underground field survey, the analysis of findings of rock fragments, mineral composition, traces of metallurgical processes ...
Schejbal, Ctirad
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

A Methodology for Afterburner Evaluation [PDF]

open access: yes, 1996
A preliminary investigation of the performance of an afterburner module proposed by the Gas Turbine Research Establishment, Bangalore for the Kaveri engine has been carried out.
Haran, AP   +6 more
core  

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