Results 151 to 160 of about 830,162 (351)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

Teachers managing the curriculum in the context of the mathematics’ subject group [PDF]

open access: yes, 2011
This study addresses the teacher daily practice. The goal is to understand, from the teachers’ perspective, the challenges and difficulties that they face when attempting to involve the pupils in mathematics learning.
Nunes, Cláudia, Ponte, João Pedro da
core  

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

open access: yesAdvanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang   +13 more
wiley   +1 more source

Vedic division methodology for high-speed very large scale integration applications

open access: yesThe Journal of Engineering, 2014
Transistor level implementation of division methodology using ancient Vedic mathematics is reported in this Letter. The potentiality of the ‘Dhvajanka (on top of the flag)’ formula was adopted from Vedic mathematics to implement such type of divider for ...
Prabir Saha   +3 more
doaj   +1 more source

A Survey of the Differential Geometry of Discrete Curves [PDF]

open access: yes, 2013
Discretization of curves is an ancient topic. Even discretization of curves with an eye toward differential geometry is over a century old. However there is no general theory or methodology in the literature, despite the ubiquitous use of discrete curves
Carroll, Daniel   +3 more
core  

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun   +11 more
wiley   +1 more source

USE OF MODERN TEACHING INFORMATION TECHNOLOGIES IN HIGHER EDUCATIONAL ESTABLISHMENTS WITH III-IV LEVELS OF ACCREDITATION

open access: yesІнформаційні технології і засоби навчання, 2010
Theoretic and practical significancy, a lack of elaboration of the methodology and the methods of the computer technologies of higher mathematics’ teaching became the reason for choosing the problem of the research, which lies in searching and ...
Liudmyla A. Hladkova, Maryna A. Naumova
doaj  

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

METHODOLOGICAL PREPARATION OF THE FUTURE TEACHER OF MATHEMATICS

open access: yes, 2023
The general pedagogical function of the teacher includes the ability to master the forms and methods of teaching, including organizing students' project activities. The labor actions of the teacher of the subject area "Mathematics" should be aimed at the formation of an informational educational environment that promotes the development of mathematical
openaire   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy