Results 151 to 160 of about 103,588 (268)

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

open access: yesAdvanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong   +21 more
wiley   +1 more source

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

open access: yesAdvanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv   +11 more
wiley   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng   +17 more
wiley   +1 more source

Simulation based new method for population variance using auxiliary information. [PDF]

open access: yesSci Rep
Ahmadini AAH   +5 more
europepmc   +1 more source

The mathematization of science: methodological aspect

open access: yesProceedings of the National Aviation University. Series: Philosophy, Cultural, 2017
openaire   +1 more source

Miniaturized 3D Magnetic Force Sensor via Laser‐Assisted Folding and Magnetization for Enhanced Robotic Dexterity

open access: yesAdvanced Science, EarlyView.
To achieve 3D force sensing in confined spaces such as fingertips, we developed a laser‐assisted folding and magnetization method to fabricate miniature films with precise centripetal magnetization. The resulting compact sensor delivers high force resolution, rapid response, and long‐term stability, significantly enhancing the manipulation capabilities
Yujie Huang   +10 more
wiley   +1 more source

A Large‐Area Broadband Multimodal Dual‐Resonant Haptic Device for Bidirectional Telerobotic and Augmented Interactions

open access: yesAdvanced Science, EarlyView.
We present a large‐area bidirectional human–machine interface integrating electrostatic multimodal tactile sensing with a dual‐resonant haptic actuator. The system enables linear pressure sensing that is decoupled from actuation and stable broadband vibrotactile feedback under dynamic contact conditions, supporting real‐time feedback modulation aligned
Jihun Son   +16 more
wiley   +1 more source

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