Results 51 to 60 of about 1,465,762 (307)

Journal of Methodology of Social Sciences and Humanities (MSSH);114

The main objective of Methodology of Humanities and Social Sciences (MSSH) is to provide an intellectual platform for national and international researchers to discuss their most recent findings related to philosophical foundations and methodology of ...
Methodology of Social Sciences and Humanities, J (via Mendeley Data)
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Screenathon 2.0: human–AI collaborative screening applied to patient-generated health data

Scientific Reports
Systematic reviews are essential for evidence-based research, yet the traditional screening process is time-consuming and difficult to scale. Human-only screening can introduce inconsistency, while fully automated approaches employing Large Language ...
Jonas Bergmann, Tiago Azzi, Rutger Neeleman, Kianush Monschau, Berke Yazan, Elena Jalsovec, Emily Westerbeek, Felix Weijdema, Jonathan de Bruin, Qixiang Fang, Rens van de Schoot   +10 more
doaj   +1 more source

Journal of Methodology of Social Sciences and Humanities; No. 111

Study of the relationship between philosophy, philosophy of social sciences and humanities, methodology and research method; The role of philosophy and methodology of social sciences and humanities in the quantitative and qualitative improvement of ...
Methodology of Social Sciences and Humanities, J (via Mendeley Data)
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Understanding and optimising patient and public involvement in trial oversight: an ethnographic study of eight clinical trials

Trials, 2020
Background Trial oversight is important for trial governance and conduct. Patients and/or lay members of the public are increasingly included in trial oversight committees, influenced by international patient and public involvement (PPI) initiatives to ...
K. D. Coulman, A. Nicholson, A. Shaw, A. Daykin, L. E. Selman, R. Macefield, G. W. Shorter, H. Cramer, M. R. Sydes, C. Gamble, M. E. Pick, G. Taylor, J. A. Lane   +12 more
doaj   +1 more source

Journal of Methodology of Social Sciences and Humanities; No. 108

Study of the relationship between philosophy, philosophy of social sciences and humanities, methodology and research method; The role of philosophy and methodology of social sciences and humanities in the quantitative and qualitative improvement of the ...
Methodology of Social Sciences and Humanities, J (via Mendeley Data)
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Evaluating the construct validity of text embeddings with application to survey questions

EPJ Data Science, 2022
Text embedding models from Natural Language Processing can map text data (e.g. words, sentences, documents) to meaningful numerical representations (a.k.a. text embeddings).
Qixiang Fang, Dong Nguyen, Daniel L. Oberski   +2 more
doaj   +1 more source

Journal of Methodology of Social Sciences and Humanities; No.94

Study of the relationship between philosophy, philosophy of social sciences and humanities, methodology and research method; The role of philosophy and methodology of social sciences and humanities in the quantitative and qualitative improvement of ...
Methodology of Social Sciences and Humanities, J (via Mendeley Data)
core   +1 more source