Results 31 to 40 of about 96,874 (263)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

METHODS OF ITS TEACHING IN THE SCIENTIFIC AND METHODOLOGICAL LITERATURE

open access: yes, 2022
This article provides information about the role of words in our language and their use in many senses, as well as the types of use, the most common methods of semantic transfer in our speech. In addition, the works of our great linguists provide theoretical information and their views on the transfer of meaning, as well as on the means of increasing ...
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

WHAT IS THE TRICK? (A SECONDARY SCHOOL LESSON ON THE CREATIVE ACTIVITY OF M.YA. BORODITSKAYA)

open access: yesФилологический класс, 2019
The article describes a lesson-portrait model which deals with works of modern poetess Marina Boroditskaya and considers an approach to studying the poems of the poetess in the basic course of literature (after learning mythology in grades 6-7).
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

THE THEME OF CREATIVITY/POETRY IN CONTEMPORARY LYRICS: A DRAFT LESSON PLAN FOR HIGH SCHOOL CLASSES

open access: yesФилологический класс, 2019
The author of the article argues that a discussion in high school literature classes of contemporary Russian lyrical poetry that includes intertextual allusions to the literature of earlier periods is a means to stimulate a thoughtful, “philological ...
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Identities and writing practices in teaching experiences

open access: yesPoligramas, 2021
This article analyzes lectures by teachers in the area of Language and Literature sustained in the workshops of the Colombian Network for the Transformation of Teacher Training in Language. As a methodology, educational ethnography is used in
Mery Cruz Calvo
doaj   +1 more source

Identification of Literacy Teaching Methods in Georgian Methodological Literature

open access: yes,,INTERCULTURAL DIALOGUES“ TRANSACTIONS, 2021
One of the main and key issues of language mastery is the study of literacy in this language. The issues of identification and classification of literacy teaching methods have always been in the center of attention in the Georgian methodological literature. All methods used in teaching Georgian literacy can be conditionally divided into three groups: a)
openaire   +2 more sources

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

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