Results 1 to 10 of about 1,906,701 (120)
Molecular methods used in clinical laboratory: prospects and pitfalls [PDF]
FEMS Immunology & Medical Microbiology, 2007 The role of molecular detection, identification and typing or fingerprinting of microorganisms has shifted gradually from the academic world to the routine diagnostic laboratory. Molecular methods have been used increasingly over the past decade to improve the sensitivity, specificity and turn-around time in the clinical laboratory.
Muhammad G, Morshed +3 more
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Workshop on laboratory protocol standards for the molecular methods database
New Biotechnology, 2013 Management of data to produce scientific knowledge is a key challenge for biological research in the 21st century. Emerging high-throughput technologies allow life science researchers to produce big data at speeds and in amounts that were unthinkable just a few years ago.
Klingström, Tomas +11 more
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Laboratory Methods in Molecular Epidemiology: Bacterial Infections
Microbiology Spectrum, 2018 ABSTRACTIn infectious disease epidemiology, the laboratory plays a critical role in diagnosis, outbreak investigations, surveillance, and characterizing biologic properties of microbes associated with their transmissibility, resistance to anti-infectives, and pathogenesis.
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Laboratory Methods in Molecular Epidemiology: Viral Infections
Microbiology Spectrum, 2018 ABSTRACT Viruses, which are the most abundant biological entities on the planet, have been regarded as the “dark matter” of biology in the sense that despite their ubiquity and frequent presence in large numbers, their detection and analysis are not always straightforward.
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Molecular methods in the laboratory diagnosis of sexually transmitted infections
Indian Journal of Sexually Transmitted Diseases and AIDS, 2015 Sexually transmitted infections (STIs) are a public health problem, and their prevalence is rising even in developed nations, in the era of HIV/AIDS. While the consequences of STIs can be serious, the good news is that many of these complications are preventable if appropriate screening is done in high-risk individuals, when infection is strongly ...
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Two-laboratory collaborative study on identification of mycobacteria: molecular versus phenotypic methods [PDF]
Journal of Clinical Microbiology, 1996 Previous studies have indicated that the conventional tests used for the identification of mycobacteria may (i) frequently result in erroneous identification and (ii) underestimate the diversity within the genus Mycobacterium. To address this issue in a more systematic fashion, a study comparing phenotypic and molecular methods for the identification ...
B, Springer +4 more
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Identification of Burkholderia spp. in the Clinical Microbiology Laboratory: Comparison of Conventional and Molecular Methods [PDF]
Journal of Clinical Microbiology, 1999 ABSTRACT Cystic fibrosis (CF) predisposes patients to bacterial colonization and infection of the lower airways. Several species belonging to the genus Burkholderia are potential CF-related pathogens, but microbiological identification may be complicated.
van Pelt, C +8 more
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Selecting a SARS-CoV-2/COVID Molecular Testing Method for Your Laboratory [PDF]
The Journal of Applied Laboratory Medicine, 2020 In early March 2020 it became apparent that clinical laboratories would need to quickly develop strategies for SARS-CoV-2/COVID-19 testing. For most, the initial approach was to send out testing to a reference laboratory. As the pandemic has progressed, the food and drug administration (FDA) has allowed for several manufacturers to make testing ...
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The Journal of Infection in Developing Countries, 2016 Introduction: Diarrheal disease due to toxigenic Clostridium difficile (CD) accounts for an increased number of hospitalizations and deaths each year. Published guidelines recommend reflex testing of CD antigen-positive samples to molecular testing or testing samples directly by a molecular assay.
Diane C Halstead +5 more
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The performance of four molecular methods for the laboratory diagnosis of congenital toxoplasmosis in amniotic fluid samples [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2013 Toxoplasmosis may be life-threatening in fetuses and in immune-deficient patients. Conventional laboratory diagnosis of toxoplasmosis is based on the presence of IgM and IgG anti-Toxoplasma gondii antibodies; however, molecular techniques have emerged as alternative tools due to their increased sensitivity.
Teixeira, Leandro Emidio +7 more
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