Results 141 to 150 of about 5,149,886 (244)

Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study. [PDF]

Asia Pac J Clin Nutr
Chang S, Shi K, Zhang M.
europepmc   +1 more source

MARKETING RESEARCH TECHNIQUES OF SMALL- TO MEDIUM-SIZED FOOD PROCESSORS IN THE PACIFIC NORTHWEST

Research Methods/ Statistical Methods,
Johnson, Aaron J., Vega-H, Esteban
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Concerns About Heterogeneity Assessment in Statistics of Meta-analyses; a Letter to the Editor. [PDF]

Arch Acad Emerg Med
Karami M, Farrokhi M.
europepmc   +1 more source

USING ABSOLUTE DEVIATIONS TO COMPUTE LINES OF BEST FIT

Research Methods/ Statistical Methods,
Houck, James P., Hunt, R.D.
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Causal effect estimation from trans-regulatory single-cell CRISPR screens. [PDF]

Cell Genom
Christensen OP, Markham A, Kang H, Gabriel E, Pers TH.   +4 more
europepmc   +1 more source

SEQUENTIAL REGRESSION: A FLEXIBLE TOOL FOR TIME SERIES MODELING

Research Methods/ Statistical Methods,
Fackler, Paul L., King, Robert P.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Gut Microbiota Alterations Associated With Colonization by Multidrug-Resistant Organisms in ICU Patients: First Systematic Review and Meta-Analysis. [PDF]

Microbiologyopen
Goicea AE, Leucuța DC, Bodolea C.
europepmc   +1 more source