Results 201 to 210 of about 63,025,606 (387)

A method for satellite time series anomaly detection based on fast-DTW and improved-KNN

open access: hybrid, 2022
Langfu Cui   +6 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Machine learning methods to support personalized neuromusculoskeletal modelling

open access: green, 2020
David J. Saxby   +17 more
openalex   +2 more sources

Path Loss Prediction Based on Machine Learning Methods for Aircraft Cabin Environments [PDF]

open access: gold, 2019
Jinxiao Wen   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

PLAID: ultrafast single-sample gene set enrichment scoring. [PDF]

open access: yesBioinformatics
Zito A   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy