Results 41 to 50 of about 14,063,414 (314)

Towards a Deep Automatic Generation of Figure-ground Maps [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Figure-ground maps play a key role in many disciplines where urban planning or analysis is involved. In this context, the automatic generation of such maps with respect to certain requirements and constraints is an important task.
L. Arzoumanidis, J. Hecht, Y. Dehbi
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Unveiling the social fabric through a temporal, nation-scale social network and its characteristics

Scientific Reports
Social networks shape individuals’ lives, influencing everything from career paths to health. This paper presents a registry-based, multi-layer and temporal network of the entire Danish population from 2008 to 2021.
Jolien Cremers, Benjamin Kohler, Benjamin Frank Maier, Stine Nymann Eriksen, Johanna Einsiedler, Frederik Kølby Christensen, Sune Lehmann, David Dreyer Lassen, Laust Hvas Mortensen, Andreas Bjerre-Nielsen   +9 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

CFD Simulation of an Industrial Dust Cyclone Separator: A Comparison with Empirical Models: The Influence of the Inlet Velocity and the Particle Size on Performance Factors in Situation of High Concentration of Particles

Journal of Engineering
The present work is dedicated to the study of multiphase turbulent and three-dimensional rotational flow in dust cyclones, a contribution to air pollution control.
Tchinda Vermande Paganel, Epee Fabrice Alban, Mezoue Adiang Cyrille, Claude Valery Ngayihi Abbe   +3 more
doaj   +1 more source

Application of the target trial emulation framework to external comparator studies

Frontiers in Drug Safety and Regulation
External comparator (EC) studies are increasingly being used to generate evidence that supports the evaluation of emerging pharmacological treatments for regulatory and health technology assessment (HTA) purposes.
Kellyn Arnold, Luis Antunes, Briana Coles, Hopin Lee   +3 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Method in Galen.

Dynamis (Granada, Spain), 1995
I have discussed the four methods of ancient philosophy namely demonstration, division, resolution, and composition. But first, I glance at logic, which "discovers the principles of medical treatment". Method in pathology discovers "the affected parts of the body" and nosology, "the symptoms of diseases and their causes".
openaire   +7 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source