Results 61 to 70 of about 43,024,139 (304)

SpiDa-MRI: behavioral and (f)MRI data of adults with fear of spiders

Scientific Data
Neuroimaging has greatly improved our understanding of phobic mechanisms. To expand on these advancements, we present data on the heterogeneity of neural patterns in spider phobia combined with various psychological dimensions of spider phobia, using ...
Mengfan Zhang, Alexander Karner, Kathrin Kostorz, Sophia Shea, David Steyrl, Filip Melinscak, Ronald Sladky, Cindy Sumaly Lor, Frank Scharnowski   +8 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Iterative methods improving newton's method by the decomposition method

Computers & Mathematics with Applications, 2005
In order to solve a scalar nonlinear equation \(f(x)=0\), the author constructs a sequence of higher-order iterative methods of Newton-type by applying the so called Adomian's decomposition method, see \textit{G. Adomian} and \textit{R. Rach} [Math. Anal. Appl. 105, 141--166 (1985; Zbl 0552.60060)].
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Strategies to implement evidence-informed decision making at the organizational level: a rapid systematic review

BMC Health Services Research
Background Achievement of evidence-informed decision making (EIDM) requires the integration of evidence into all practice decisions by identifying and synthesizing evidence, then developing and executing plans to implement and evaluate changes to ...
Emily C. Clark, Trish Burnett, Rebecca Blair, Robyn L. Traynor, Leah Hagerman, Maureen Dobbins   +5 more
doaj   +1 more source

Abrupt transitions in time series with uncertainties

Nature Communications, 2018
Most time series techniques tend to ignore data uncertainties, which results in inaccurate conclusions. Here, Goswami et al. represent time series as a sequence of probability density functions, and reliably detect abrupt transitions by identifying ...
Bedartha Goswami, Niklas Boers, Aljoscha Rheinwalt, Norbert Marwan, Jobst Heitzig, Sebastian F. M. Breitenbach, Jürgen Kurths   +6 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Mitigating Water Salinity in the Jordan Valley: Experimental Evidence for the Effectiveness of Electronic Water Treatment on Irrigation Water Quality and Crop Productivity

Advances in Agriculture
Water salinity is a major challenge for Jordanian farmers in the Jordan Valley negatively impacting crop yield and soil health. One potential solution to this issue is electronic water treatment (EWT): a novel technology that uses radio wave ...
Samer Talozi, Ammar Namarneh, William Thompson, Sewar Salah   +3 more
doaj   +1 more source

Promoting awareness of key resources for evidence-informed decision making in public health: An evaluation of a webinar series about knowledge translation methods and tools

Frontiers in Public Health, 2016
The National Collaborating Centre for Methods and Tools (NCCMT) has developed several resources to support evidence-informed decision making – the process of distilling and disseminating best available evidence from research, context and experience – and
Jennifer eYost, Jeannie eMackintosh, Kristin eRead, Maureen eDobbins   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source