Results 61 to 70 of about 63,025,606 (387)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Unveiling the social fabric through a temporal, nation-scale social network and its characteristics

open access: yesScientific Reports
Social networks shape individuals’ lives, influencing everything from career paths to health. This paper presents a registry-based, multi-layer and temporal network of the entire Danish population from 2008 to 2021.
Jolien Cremers   +9 more
doaj   +1 more source

Towards a Deep Automatic Generation of Figure-ground Maps [PDF]

open access: yesISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Figure-ground maps play a key role in many disciplines where urban planning or analysis is involved. In this context, the automatic generation of such maps with respect to certain requirements and constraints is an important task.
L. Arzoumanidis, J. Hecht, Y. Dehbi
doaj   +1 more source

Chaplygin's method is Newton's method

open access: yesJournal of Mathematical Analysis and Applications, 1978
This method has been extended to ordinary differential equations in [w” by Lusin [6], to ordinary differential equations in Banach spaces by Mlak [8] and to parabolic equations by Mlak [7] and Szarki [15, Sect. 661. In each case a different type of hypotheses is assumed. A formal generalization considered by Wazewski [18] has been found by Schelkunoff [
openaire   +3 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

CFD Simulation of an Industrial Dust Cyclone Separator: A Comparison with Empirical Models: The Influence of the Inlet Velocity and the Particle Size on Performance Factors in Situation of High Concentration of Particles

open access: yesJournal of Engineering
The present work is dedicated to the study of multiphase turbulent and three-dimensional rotational flow in dust cyclones, a contribution to air pollution control.
Tchinda Vermande Paganel   +3 more
doaj   +1 more source

Application of the target trial emulation framework to external comparator studies

open access: yesFrontiers in Drug Safety and Regulation
External comparator (EC) studies are increasingly being used to generate evidence that supports the evaluation of emerging pharmacological treatments for regulatory and health technology assessment (HTA) purposes.
Kellyn Arnold   +3 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Iterative methods improving newton's method by the decomposition method

open access: yesComputers & Mathematics with Applications, 2005
In order to solve a scalar nonlinear equation \(f(x)=0\), the author constructs a sequence of higher-order iterative methods of Newton-type by applying the so called Adomian's decomposition method, see \textit{G. Adomian} and \textit{R. Rach} [Math. Anal. Appl. 105, 141--166 (1985; Zbl 0552.60060)].
openaire   +2 more sources

An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies

open access: yesMultivariate Behavioral Research, 2011
The propensity score is the probability of treatment assignment conditional on observed baseline characteristics. The propensity score allows one to design and analyze an observational (nonrandomized) study so that it mimics some of the particular ...
P. Austin
semanticscholar   +1 more source

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