Results 141 to 150 of about 1,090,569 (315)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
COMPETITIVE MECHANISMS FOR FINANCING INNOVATION AND INVESTMENT PROJECTS
Модернизация, инновация, развитие, 2016 The article deals with the organizational and methodological basis for the formation of competitive technologies and innovative fi nancing mechanisms and investment projects.
N. I. Komkov +3 more
doaj
Genetic and memetic algorithms for scheduling railway maintenance activities
Nowadays railway companies are confronted with high infrastructure maintenance costs. Therefore good strategies are needed to carry out these maintenance activities in a most cost effective way.
Dekker, R., Kaymak, U., Budai-Balke, G.
core
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Classical Methods and Calculation Algorithms for Determining Lime Requirements
Revista Brasileira de Ciência do SoloThe methods developed for determination of lime requirements (LR) are based on widely accepted principles. However, the formulas used for calculation have evolved little over recent decades, and in some cases there are indications of their inadequacy ...
André Guarçoni +1 more
doaj +1 more source
Higher-order finite-difference methods for partial differential equations
, 1997 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis develops two families of numerical methods, based upon rational approximations having distinct real poles, for solving first- and second-order ...
Cheema, Tasleem Akhter, Cheema, T.A.
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New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
Evolutionary algorithms in artificial intelligence: a comparative study through applications [PDF]
, 1994 For many years research in artificial intelligence followed a symbolic paradigm which required a level of knowledge described in terms of rules. More recently subsymbolic approaches have been adopted as a suitable means for studying many problems.
Nettleton, David John, Nettleton, D.J
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
PASSWORD HASHING METHODS AND ALGORITHMS ON THE .NET PLATFORM
Сучасні інформаційні системиWeb applications, which are widely used to provide services and collect information, have become a major target for attackers, especially with the emergence of government services that process sensitive data.
Volodymyr Fedorchenko +4 more
doaj +1 more source