Results 151 to 160 of about 7,623,582 (351)

A Missing Link in the Chaîne Opératoire

EXARC Journal
How elitist attitudes shape archaeological interpretations. A curious misunderstanding arose while writing about Bronze Age metalworking hearths and smiths.
E. Giovanna Fregni
doaj  

Methods and Techniques to Facilitate the Development of Clostridium novyi NT as an Effective, Therapeutic Oncolytic Bacteria. [PDF]

Front Microbiol, 2021
Dailey KM, Jacobson RI, Johnson PR, Woolery TJ, Kim J, Jansen RJ, Mallik S, Brooks AE.   +7 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Knowledge mobilisation strategies and techniques

, 2014
This talk was presented at the 6th ESRC Research Methods Festival in July ...
Gagnon, Emily, Hart, Angie
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Portfolio Planning Methods: Faulty Approach or Faulty Research? A Rejoinder to 'Making Better Decisions' by Wensley [PDF]

Wensley (1994) makes three key points. First, it is worthwhile to conduct empirical studies of the value of management techniques. Second, managers probably misuse portfolio methods. Third, the Armstrong and Brodie study is flawed.
JS Armstrong, Roderick J. Brodie
core  

Book Review: Recent Publications: Experimental Archaeology in the November 2015 Issue of the Cambridge Archaeological Journal (Volume 25, Issue 4)

EXARC Journal, 2016
In the last quarter of the 1900s, John Coles (1979) and Peter Reynolds (1999) introduced the subject of experimental archaeology, which has gained significant momentumin the past few years.
E. Giovanna Fregni
doaj  

Recovery of the patient with plantar fasciitis using methods and techniques from physiotherapy

Annals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement
The present work aims to demonstrate the importance of physical therapy in a rehabilitation program for patients with plantar fasciitis. Due to its frequency and the problems, it creates, related to the difficulty of working.
Benedek Florian
doaj   +1 more source

Starch and Glycogen Analyses: Methods and Techniques. [PDF]

Biomolecules, 2020
Brust H, Orzechowski S, Fettke J.
europepmc   +1 more source