Results 141 to 150 of about 7,623,582 (351)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Techniques to Build and Reuse Assets

open access: yes, 2008
technique. Section 7.7 describes software architectures, which represent an independent research area. For most of the techniques (where appropriate), a list of enabling methodologies and technologies is presented.
Davide Brugali   +2 more
core  

Flax Fibre Extraction Techniques in the Late Middle Ages

open access: yesEXARC Journal, 2020
On its surface, linen production research is simple as there is a large corpus of books available; however, the majority of these date to the last three centuries.
Martina König
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Transmission electron microscopy in cell biology: sample preparation techniques and image information

open access: yes, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166Transmission electron microscopy is a proven technique in the field of cell biology and a very useful tool in biomedical research. Innovation and improvements in equipment together with
Cortadellas i Raméntol, Núria   +2 more
core  

Let the Chips Fall Where They May: Evaluating the Impact and Effectiveness of Video Resources for Knowledge Transfer in Flint Knapping

open access: yesEXARC Journal, 2020
Knowledge and know-how: The ‘how’ of knowledge transferal continues to be a question in prehistoric archaeology, especially in relation to early hominid development.
John Kiernan
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Gear Fault Monitoring: Comparison of Vibration Analysis Techniques

open access: yes, 1998
This paper deals with gear condition monitoring based on vibration analysis techniques. The detection and diagnostic capability of some of the most effective techniques are discussed and compared on the basis of experimental results, concerning a gear ...
DALPIAZ G   +4 more
core  

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