Results 121 to 130 of about 7,623,582 (351)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Handbook of Qualitative Research Methods on Human Resource Management: Innovative Techniques

, 2016
This Handbook explores the opportunities and challenges of new technologies for innovating data collection and data analysis in the context of human resource management.
Townsend, Keith, Lewin, David, Loudoun, Rebecca   +2 more
core   +1 more source

A Preliminary Attempt to Reconstruct some Tools and Techniques of Ornamentation of the Comb-Pit Ware from the Site of Hepojarvi (Karelian Isthmus, Leningrad Oblast, Russia)

EXARC Journal, 2019
The site of Hepojarvi is located on the northern coast of Hepojarvi lake, near Saint Petersburg, Russia. The site is a multi-layer settlement with different types of Neolithic pottery (from Sperrings to late Comb-Pit Ware); the settlement functioned in ...
Alexander Akulov
doaj  

Methods and techniques for in vitro subcellular localization of radiopharmaceuticals and radionuclides. [PDF]

Nucl Med Biol, 2021
Costa IM, Cheng J, Osytek KM, Imberti C, Terry SYA.   +4 more
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

A CURE for Teaching Experimental Archaeology

EXARC Journal
This paper explores the ‘Course-based Undergraduate Research Experience’ (CURE) model as an effective approach to teaching experimental archaeology. While the CURE model has been successfully used in STEM fields to enhance student engagement and produce ...
Shelby S. J. Putt
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

32. MONTE CARLO TECHNIQUES

, 2008
Monte Carlo techniques are often the only practical way to evaluate difficult integrals or to sample random variables governed by complicated probability density functions.
F. James (cern, Monte Carlo Techniques
core  

The Transformation of Glass Debris from Apollonia-Arsuf (Byzantine Sozousa)

EXARC Journal
The site of Apollonia-Arsuf (Byzantine Sozousa) is located on the Mediterranean coast, some 17 km north of Jaffa (Joppa) and 34 km south of Caesarea Maritima, Israel.
Oren Tal, Ruth E. Jackson-Tal, Dafna Kaffeman   +2 more
doaj  

The challenge of exercise (non-)adherence: a scoping review of methods and techniques applied to improve adherence to physical activity and exercise in people with inflammatory arthritis. [PDF]

Rheumatol Adv Pract, 2023
Chaplin H, Sekhon M, Godfrey E.
europepmc   +1 more source