Results 61 to 70 of about 7,623,582 (351)

An Investigation of Science Teachers’ Teaching Methods and Techniques: Amasya Case

Kuramsal Eğitimbilim Dergisi, 2014
The purpose of this study is to determine the methods and techniques science teachers mostly employ in their classrooms. To collect data, the researchers employed a survey with 60 science teachers and randomly selected 6 of them to observe these selected
Orhan KARAMUSTAFAOĞLU, Adem BAYAR, Mert KAYA   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Critical review of multi-criteria decision aid methods in conceptual design phases: application to the development of a solar collector structure [PDF]

, 2014
At each stage of the product development process, the designers are facing an important task which consists of decision making. Two cases are observed: the problem of concept selection in conceptual design phases and, the problem of pre-dimensioning once
EL AMINE, Mehdi, Amine, Mehdi El, PAILHES, Jerome, PERRY, Nicolas   +3 more
core   +1 more source

Techniques and methods of characterization of admixtures for the concrete

Materiales de Construccion, 2003
Admixtures are defined as those products that are incorporated in the moment of the process of mixture of the concrete in a quantity not bigger than 5 by mass of the cement %, with relationship to the cement content in the concrete, with object of ...
M. Palacios, C. Sierra, F. Puertas
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Reinventing the Egyptian Pulley

EXARC Journal, 2014
The Egyptian pulley incorporates several novel, useful features. The design involves only significant compressive loading of its two components. The materials of construction are high compressive strength materials - limestone, granite or copper.
Stephen Blakely, Gregory Blakely
doaj  

Sampling Techniques for Kernel Methods [PDF]

, 2002
We propose randomized techniques for speeding up Kernel Principal Component Analysis on three levels: sampling and quantization of the Gram matrix in training, randomized rounding in evaluating the kernel expansions, and random projections in evaluating the kernel itself.
Achlioptas, D., McSherry, F., Schölkopf, B.   +2 more
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Density Matrix Methods in Linear Scaling Electronic Structure Theory

, 2011
We review some recursive Fermi operator expansion techniques for the calculation of the density matrix and its response to perturbations in tight-binding, Hartree-Fock, or density functional theory, at zero or finite electronic temperatures.
Niklasson, Anders,, Anders M. N. Niklasson   +1 more
core   +1 more source