Results 71 to 80 of about 147,072 (297)
Methods and Applications in Trapped Charge Dating
Trapped charge dating is a commonly used chronological tool in Earth Sciences and Archaeology. The two principle methods are luminescence dating and electron spin resonance.
James K. Feathers
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Research frontiers in geophysics are being expanded, with development of new fields resulting from technological advances such as the Earth observation satellite network, global positioning system, high pressure-temperature physics, tomographic methods ...
Jaime Urrutia-Fucugauchi +1 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
New Methods for the Chemical Isolation and Stable Isotope Measurement of Multiple Transition Metals, with Application to the Earth Sciences [PDF]
Mingzhao Sun, Corey Archer, Derek Vance
openalex +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Opportunities and challenges of geo-spatial information science from the perspective of big data
The era of big data has arrived, and it has penetrated every aspect of human life.As the geo-spatial information science spawned by the intersection of earth sciences and information sciences, the advent of the era of big data provides it with richer ...
Deren LI +4 more
doaj
BACKGROUND In recent years, whole-rock inductively coupled plasma-mass spectrometry (ICP-MS) trace and in situ laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) trace element analyses have been increasingly more widely used in the ...
GUO Dong-xu +4 more
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