Results 91 to 100 of about 119,491,879 (244)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Causality for Earth Science -- A Review on Time-series and Spatiotemporal Causality Methods
CoRRThis survey paper covers the breadth and depth of time-series and spatiotemporal causality methods, and their applications in Earth Science. More specifically, the paper presents an overview of causal discovery and causal inference, explains the underlying causal assumptions, and enlists evaluation techniques and key terminologies of the domain area ...
Sahara Ali +7 more
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
7th World Multidisciplinary Earth Sciences Symposium– WMESS2021
, 2021 7th World Multidisciplinary Earth Sciences Symposium ...
Yılmaz, Işık
core +1 more source
International Journal of Nanomedicine, 2011 Eriko Kasuga1,2, Yoshiyuki Kawakami2,3, Takehisa Matsumoto1, Eiko Hidaka1, Kozue Oana2, Naoko Ogiwara1, Dai Yamaki4, Tsukasa Sakurada4, Takayuki Honda1,51Department of Laboratory Medicine, Shinshu University Hospital, 2Division of Infection Control and ...
Kasuga E +8 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
UMD Earth and Environmental Sciences Newsletter for Alumni & Friends (2018)
, 2018 University of Minnesota Duluth. Department of Earth and Environmental Sciences. (2018). UMD Earth and Environmental Sciences Newsletter for Alumni & Friends (2018).
University of Minnesota Duluth. Department of Earth and Environmental Sciences
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The six days and the deluge: some ideas on earth history in the Royal Society of London 1660-1775 [PDF]
, 1969 The influence of the biblical story of Creation and the Deluge on ideas of earth history during the period 1660-1775 is examined with particular reference to papers on the subject published in the Philosophical Transactions of the Royal Society of London.
Stokes, Evelyn
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Scientific Method and Earth Sciences [PDF]
Journal of Energy Resources Technology, 2006 Larry W. Lake, Steven L. Bryant
openaire +1 more source