Results 101 to 110 of about 123,307,915 (315)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Application of the finite difference method in the study of wave propagation in a borehole [PDF]

open access: yes, 1984
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1984.Microfiche copy available in Archives and Science.Bibliography: leaves 41-43.by Federico Pardo Casas.M ...
Pardo Casas, Federico
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Inverse problem for stress in the earth based on geodetic data

open access: yes, 1981
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Earth and Planetary Sciences, 1981.MICROFICHE COPY AVAILABLE IN ARCHIVES AND LINDGREN.Includes bibliographies.by Keiichiro Ikeda.Ph ...
Ikeda, Keiichiro
core  

Tidal distortion in shallow estuaries [PDF]

open access: yes, 1984
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1984.Microfiche copy available in Archives and Science.Includes bibliographies.by Paul Edward Speer.Ph ...
Speer, Paul E. (Paul Edward)
core  

Charting the course for the next decade of sustainability research and innovation

open access: yesGlobal Sustainability
Non-technical summary The Anthropocene era demands urgent societal changes as we exceed planetary limits. Addressing key sustainability and governance challenges requires inter- and transdisciplinary approaches.
G. B. Sioen   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Earth structure and earthquake locations in the Coyote Lake area, central California

open access: yes, 1981
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Earth and Planetary Sciences, 1981.MICROFICHE COPY AVAILABLE IN ARCHIVES AND LINDGREN.Bibliography: leaves 285-296.by Clifford H.
Thurber, Clifford H
core  

Chemical fractionations in solar composition material [PDF]

open access: yes, 1980
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Earth and Planetary Sciences, 1980.Microfiche copy available in Archives and Science.Bibliography: leaves 152-168.by Melvin Bruce Fegley, Jr.Ph ...
Fegley, Melvin Bruce
core  

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