Results 131 to 140 of about 20,753,610 (280)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Editorial: Advances in pediatric rehabilitation clinical trials: design, methods, and analysis. [PDF]

Front Pediatr
DeLuca SC, Darragh AR, Heathcock J.
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

STANDARD METHODS OF MILK ANALYSIS BACTERIOLOGICAL METHODS [PDF]

American Journal of Public Health, 1926
openaire   +2 more sources

Prioritizing areas for post-fire restoration in Greece using mixed-methods spatial analysis. [PDF]

PLoS One
Palenova E, Veraverbeke S, Drobyshev I, Kontos T, Ebert K.   +4 more
europepmc   +1 more source

Methods of Analysis and Identification of Betulin and Its Derivatives. [PDF]

Molecules, 2023
Takibayeva AT, Zhumabayeva GK, Bakibaev AA, Demets OV, Lyapunova MV, Mamaeva EA, Yerkassov RS, Kassenov RZ, Ibrayev MK.   +8 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Climate change and antimicrobial resistance in the Western Pacific: a mixed-methods systematic analysis. [PDF]

Lancet Reg Health West Pac
Yang L, Ma Z, Meng F, Wang R, Chen S, Liu C, Ho HC, Xu M, Chua AQ, Hsu LY, Jia Y, Zhang Y, Huang C, Ji JS.   +13 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

ICP slurry introduction for simple and rapid determination of Pb, Mg and Ca in plant roots

Open Chemistry, 2007
Barałkiewicz Danuta, Kanecka-Hanc Anetta, Gramowska Hanka   +2 more
doaj   +1 more source