Results 31 to 40 of about 1,690,442 (310)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

THE HISTORY OF RUSSIAN EMIGRATION SCHOOL IN BULGARIA: «ACADEMIC TRILOGY» OF PYOTR BITSILLI

open access: yesФилологический класс, 2017
The author of this article considers G. Petkova's monograph.
doaj   +1 more source

Features of teaching methods of Ukrainian literature during the national revival [PDF]

open access: yes, 2015
Визначено основні тенденції розвитку методики навчання української літератури в період розбудови національної школи в Україні (90-ті роки ХХ ст. – перші роки ХХІ ст.), зокрема щодо оновлення змісту шкільної літературної освіти, визначення ефективних ...
Яценко, Таміла Олексіївна
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

MODERN LITERATURE AT SCHOOL: THE LOVE TO READING

open access: yesФилологический класс, 2017
The review of the 4th literature festival “Time to Read”.
doaj   +1 more source

Teaching Language to Students with Autism [PDF]

open access: yes, 2011
This meta-synthesis of the literature on methods of instruction to students with ASD examines the various methods of teaching language to students with ASD.
Howe, Ryan
core  

Sources and Scientific Literature to the Teaching Methods of Discipline «History of Kyiv Polytechnic» [PDF]

open access: yes, 2017
В статті на основі вивчення змісту веб-порталу НТУУ «КПІ ім. Ігоря Сікорського» проаналізовано доступні групи джерел та наукову літературу для готування навчально-методичного комплексу з дисципліни «Історія Київської Політехніки».
Kostylieva, S.   +1 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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