Results 71 to 80 of about 1,995 (182)

Binding of 8-methoxypsoralen in CYP2A6 mutant active sites.

open access: yes, 2014
Side chains of amino acid residues within 5 Å of the ligand are rendered as stick figures. Red, oxygen atoms; blue, nitrogen atoms; gray, methoxsalen-complex carbon atoms; and magenta, heme group.
Chin Eng Ong (514891)   +5 more
core   +1 more source

Nanosized ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery against vitiligo: formulation optimization, in vitro evaluation and preclinical assessment

open access: yes, 2015
The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery and effective treatment against vitiligo.
Bhupinder Singh (443885)   +4 more
core   +1 more source

Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse [PDF]

open access: yes, 2009
This study addressed the hypothesis that the vestibular or lethal toxicities of allylnitrile depend on CYP2E1-mediated bioactivation. Wild-type (129S1) and CYP2E1-null male mice were exposed to allylnitrile at doses of 0, 0.5, 0.75, or 1.0 mmol/kg (po ...
Soler, Carla   +11 more
core   +1 more source

The effect of methoxsalen dose on ultraviolet-A-induced erythema

open access: yes
There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen) after ingestion of the standard dose used in photochemotherapy (psoralen plus ultraviolet A).
Farr PM; Ibbotson SH; Dawe RS
core   +4 more sources

The effect of methoxsalen dose on ultraviolet-A-induced erythema

open access: yes, 2001
There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen) after ingestion of the standard dose used in photochemotherapy (psoralen plus ultraviolet A).
Farr, Peter M.   +5 more
core   +1 more source

Method Development and Validation of Methoxsalen

open access: yesInternational Journal for Research in Applied Science and Engineering Technology, 2023
Bhagyashri S Gayke
semanticscholar   +1 more source

Phenolic Compounds of Fresh Roots and Rhizomes of Garden Angelica Angelica Archangelica L.

open access: yesInternational Journal of Secondary Metabolite, 2014
Because in the process of drying and storage of plant materials is a change of genuine compounds, we studied the content of phenolic compounds in freshly drawn angelica roots and rhizomes of the drug Angelica archangelica L. samples had been taken on the
R. M. BASHIROVA   +3 more
doaj   +2 more sources

An important cause of non-compliance. Pruritus sine materia as an adverse drug reaction

open access: yes, 1999
Pruritus without cutaneous diseases can occur as a direct adverse drug reaction of a limited number of medicines, like opioids, chloroquine, hydroxyethyl starch, gold compounds, amlodipine and methoxsalen.
Heeringa, M.   +2 more
core   +1 more source

The 8-MOP identification and isolation from the plant material and percutaneous permeation in the modified Flynn’s cell

open access: yesCurrent Issues in Pharmacy and Medical Sciences
Xanthotoxin (8-methoxypsoralen, methoxsalen) is a natural furanocoumarin consisting of coumarin annulated with furan. It’s biosynthetic route in plants continues with the activation of dimethylallylpyrophosphate (DMAPP), produced via the mevalonate ...
Elwira Sieniawska   +5 more
doaj  

Augmentation of Oral Methoxsalen-Photochemotherapy with an Oral Retinoic Acid Derivative

open access: yes, 1978
To improve the efficacy and reduce potential long-term hazards of photochemotherapy, we treated 36 patients with severe plaque-type psoriasis with a combination of oral methoxsalen-photochemotherapy (PUVA) and another oral chemotherapeutic agent, a ...
Jaschke, Erna.   +3 more
core   +1 more source

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