Results 11 to 20 of about 5,084 (189)

Real world safety of methoxyflurane analgesia in the emergency setting: a comparative hybrid prospective-retrospective post-authorisation safety study [PDF]

BMC Emergency Medicine, 2023
Background Low-dose analgesic methoxyflurane (Penthrox®) was approved in Europe for emergency relief of moderate to severe pain in conscious adults with trauma in 2015. A comparative post-authorisation safety study (PASS) was conducted to assess the risk
Nawab Qizilbash, Himanshu Kataria, Heather Jarman, Ben Bloom, Michelle Bradney, Maggie Oh, Sue Anne Yee, Ana Roncero, Ignacio Mendez, Stuart Pocock   +9 more
doaj   +3 more sources

Pain Management with Inhalation of Methoxyflurane Administrated by Non-Medical Ski Patrol: A Quality Assessment Study [PDF]

Pain and Therapy, 2023
Introduction Pain management can be challenging, especially in remote locations where first responders are not certified health care personnel. In these settings, traditional intravenous administration of analgesics is not feasible.
Hanna Sofia Rydlöv, Lars Olav Fjose, Fridtjof Heyerdahl   +2 more
doaj   +3 more sources

Haemodynamic effects of methoxyflurane versus fentanyl and placebo in hypovolaemia: a randomised, double-blind crossover study in healthy volunteers [PDF]

BJA Open, 2023
Background: Methoxyflurane is approved for relief of moderate to severe pain in conscious adult trauma patients: it may be self-administrated and is well suited for use in austere environments.
Lars Øivind Høiseth, Lars Olav Fjose, Jonny Hisdal, Marlin Comelon, Leiv Arne Rosseland, Harald Lenz   +5 more
doaj   +3 more sources

MetoksyKval: the extent of pre-hospital methoxyflurane administration for acute traumatic pain: focus on economic impact and rationale for use [PDF]

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Effective pain management is critical in pre-hospital care, yet many patients still receive suboptimal treatment. Methoxyflurane, a handheld self-administered analgesic, is increasingly used in European ambulance services.
Randi Simensen, Live Smalberget, Fridtjof Heyerdahl   +2 more
doaj   +3 more sources

Usability and effectiveness of inhaled methoxyflurane for prehospital analgesia - a prospective, observational study

BMC Emergency Medicine, 2022
Background Pain relief in the prehospital setting is often insufficient, as the administration of potent intravenous analgesic drugs is mostly reserved to physicians. In Australia, inhaled methoxyflurane has been in routine use by paramedics for decades,
Helmut Trimmel, Alexander Egger, Reinhard Doppler, Mathias Pimiskern, Wolfgang G. Voelckel   +4 more
doaj   +2 more sources

Evaluation of the effectiveness and costs of inhaled methoxyflurane versus usual analgesia for prehospital injury and trauma: non-randomised clinical study

BMC Emergency Medicine, 2022
Background We aimed to investigate clinical benefits and economic costs of inhaled methoxyflurane when used by ambulance staff for prehospital emergency patients with trauma.
Murray D. Smith, Elise Rowan, Robert Spaight, Aloysius N. Siriwardena   +3 more
doaj   +2 more sources

Analgesic effectiveness of methoxyflurane inhaler during genicular nerve block in knee osteoarthritis: a randomized controlled trial. [PDF]

Reg Anesth Pain Med
Background Up to 30% of patients with knee osteoarthritis (KOA) have evidence of sensitization, with a similar proportion experiencing severe pain during procedures.
Sawang S, Kimpee P, Itthichaikulthol W, Tontisirin N, Limpoon S, Seangrung R, Pasutharnchat K, Cohen SP.   +7 more
europepmc   +2 more sources

Comparison of inhaled methoxyflurane versus procedural sedation for manipulation and reduction of acute shoulder and elbow dislocation in the emergency department

Proceedings of Singapore Healthcare, 2022
Introduction: This paper compares the usage of inhaled methoxyflurane versus traditional procedural sedation and analgesia for manipulation and reduction of acute shoulder dislocation and acute elbow dislocation in the emergency department. Methods: This
Shu Fang Ho, Sameera Ganti, Eunizar Omar, Sherman Wei Qiang Lian, Hui Cheng Tan, Yogeswary Pasupathy, Norizan Jaafar, Faraz Zarisfi, Marcus Eng Hock Ong   +8 more
doaj   +2 more sources

Non-interventional study evaluating exposure to inhaled, low-dose methoxyflurane experienced by hospital emergency department personnel in France

BMJ Open, 2020
ObjectivesLow-dose methoxyflurane is a non-opioid, inhaled analgesic administered via the Penthrox inhaler and was recently licensed in Europe for emergency relief of moderate-to-severe trauma-associated pain in conscious adults.
John Frangos, Anissa Belbachir, Sandrine Dautheville, Christiane Jung, Key Herklotz, Freya Amon, Sara Dickerson, Berangere Chomier   +7 more
doaj   +2 more sources

Methoxyflurane for Relief of Procedural Pain in Burn Patients: A Prospective Single-Centre Evaluation Study

European Burn Journal, 2022
Background: Procedural pain in burn patients continues to be a major problem. Frequently used analgesics, such as opioids, may have various side effects, including respiratory depression, nausea, and vomiting.
Andreas Creutzburg, Martin R. Vestergaard, Pernille Pape, Caroline Hjelmdal, Filip Rangatchew, Rikke Holmgaard, Lars S. Rasmussen   +6 more
doaj   +2 more sources