The analgesia of methoxyflurane [PDF]
A preliminary study was made of analgesia produced by methoxyflurane in oxygen in eleven patients undergoing surgery. Methoxyflurane was found to be safe and excellent as an analgesic agent. An associated drowsiness was also noticed, similar to that seen in the postanaesthetic period of conventional methoxyflurane anaesthesia.
exaly +3 more sources
Sossio Serra,1 Antonio Voza,2 Germana Ruggiano,3 Andrea Fabbri,4 Elisabetta Bonafede,5 Antonella Sblendido,6 Amedeo Soldi,6 Alberto Farina6 On behalf of the MEDITA Study Group1Emergency Department, Maurizio Bufalini Hospital, Cesena, Italy; 2Emergency ...
Serra S +7 more
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Comparison of three regimens with inhalational methoxyflurane versus intranasal fentanyl versus intravenous morphine in pre-hospital acute pain management: study protocol for a randomized controlled trial (PreMeFen) [PDF]
Background Pre-hospital pain management has traditionally been performed with intravenous (IV) morphine, but oligoanalgesia remain a recognized problem.
Randi Simensen +5 more
doaj +2 more sources
Acute pain management in older adults presenting to the emergency department: a clinical review [PDF]
Managing acute pain in older adults is a complex challenge in emergency care, influenced by age-related physiological changes, multimorbidity and altered pharmacokinetics.
Sirasa Kampan +4 more
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Role of Inhaled Methoxyflurane in the Management of Acute Trauma Pain
Andrea Fabbri,1 Germana Ruggiano,2 Sergio Garcia Collado,3 Agnes Ricard-Hibon,4 Umberto Restelli,5,6 Giovanni Sbrana,7 Franco Marinangeli,8 Alberto Farina,9 Frank Coffey10 1Department of Emergency Medicine, Morgagni-Pierantoni Hospital, Forlì ...
Fabbri A +8 more
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Inhaled methoxyflurane (Penthrox) use in the outpatient and ambulatory setting: a systematic review [PDF]
Objective We assessed whether Penthrox (methoxyflurane) can provide better pain relief for elective, outpatient interventional procedures compared with other methods of pain control.Design Systematic review.Data sources Cochrane Central Register of ...
Paul Smith +3 more
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Inhaled methoxyflurane for fracture reduction in prehospital extremity trauma: an observational review of HEMS clinical practice [PDF]
Background Prehospital manipulation and reduction (M&R) of traumatic limb injuries may be required before transfer to restore alignment, reduce pain and bleeding, and limit secondary neurovascular compromise.
Joe Dowsing +3 more
doaj +2 more sources
The role of inhaled methoxyflurane in acute pain management
Keith M Porter,1 Anthony D Dayan,2 Sara Dickerson,3 Paul M Middleton4,5 1Trauma Department, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, UK; 2Independent Consultant, London, UK; 3Medical Affairs, Mundipharma
Porter KM +3 more
doaj +2 more sources
Keith M Porter,1 Mohd Kashif Siddiqui,2 Ikksheta Sharma,2 Sara Dickerson,3 Alice Eberhardt4 1University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; 2Parexel International Ltd, Chandigarh, India; 3Mundipharma International Ltd, Cambridge ...
Porter KM +4 more
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Methoxyflurane (Penthrox®)—a case series of use in the prehospital setting
Methoxyflurane (Penthrox®) is a fluorinated hydrocarbon, which when first used in general anaesthesia was noted to have strong analgesic properties in subanaesthetic dosage.
M. Forrest, K. Porter, J. Velde
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