Results 21 to 30 of about 52,767 (240)

Ku80 cooperates with CBP to promote COX-2 expression and tumor growth. [PDF]

open access: yes, 2015
Cyclooxygenase-2 (COX-2) plays an important role in lung cancer development and progression. Using streptavidin-agarose pulldown and proteomics assay, we identified and validated Ku80, a dimer of Ku participating in the repair of broken DNA double ...
Chen, Yiming   +23 more
core   +3 more sources

Aniline incorporated silica nanobubbles [PDF]

open access: yes, 2006
We report the synthesis of stearate functionalized nanobubbles of SiO2 with a few aniline molecules inside, represented as C6H5NH2@SiO2@stearate, exhibiting fluorescence with red-shifted emission.
A Blaaderen Van   +44 more
core   +3 more sources

Design, Synthesis and Antiproliferative Evaluation of Bis-Indole Derivatives with a Phenyl Linker: Focus on Autophagy

open access: yesMolecules, 2022
This work deals with the study of the synthesis of new bis-indole analogues with a phenyl linker derived from indole phytoalexins. Synthesis of target bis-indole thiourea linked by a phenyl linker was achieved by the reaction of [1-(tert-butoxycarbonyl ...
Marianna Budovska   +4 more
doaj   +1 more source

Preparation of new type of organocatalysts having a carbohydrate scaffold [PDF]

open access: yes, 2014
The synthesis of nine new, bifunctional organocatalysts having carbohydrate scaffolds has been accomplished. In these catalysts both of the catalytic amino and thiourea functions are directly attached to a carbohydrate core.
Fügedi, Péter, Ágoston, Károly
core   +1 more source

New histone deacetylase inhibitors as potential therapeutic tools for advanced prostate carcinoma [PDF]

open access: yes, 2008
The anti-epileptic drug valproic acid is also under trial as an anti-cancer agent due to its histone deacetylase (HDAC) inhibitory properties. However, the effects of valproic acid (VPA) are limited and concentrations required for exerting anti ...
Atmaca, Akin   +8 more
core   +1 more source

The Effect of Two Types of Biochars on the Efficacy, Emission, Degradation, and Adsorption of the Fumigant Methyl Isothiocyanate

open access: yesEnergies, 2016
Biochar (BC) is increasingly applied in agriculture; however, due to its adsorption and degradation properties, biochar may also affect the efficacy of fumigant in amended soil. Our research is intended to study the effects of two types of biochars (BC-1
Wensheng Fang   +8 more
doaj   +1 more source

Anti-Cancer Effect of a New 5-FU Derivative Containing Triazole-Bearing Mannose (5-FUD-MAN) Against Human Breast Cancer Cells Through LC3B-Mediated Cell Death. [PDF]

open access: yesJ Biochem Mol Toxicol
The anticancer activity of 5‐FU modified with mannose containing 1,2,3‐triazole compound in MCF‐7 breast cancer cells were revealed in this study. While 5‐FU caused cytotoxicity in both cancerous and healthy cells, 5‐FUD‐Man showed selective cytotoxicity.
Şanci E   +7 more
europepmc   +2 more sources

Effect of stevia supplementation of kale juice spheres on their quality changes during refrigerated shelf life [PDF]

open access: yes, 2018
Kale is a vegetable with high contents of health–promoting compounds although its consumption as a beverage is highly limited due to its bitter flavour. Nonetheless, the bitter flavour of Brassicas may be masked by sweetening.
Artés Calero, Francisco   +4 more
core   +2 more sources

Convenient Synthesis of Thiohydantoins, Imidazole-2-thiones and Imidazo[2,1-b]thiazol-4-iums from Polymer-Supported α-Acylamino Ketones

open access: yesMolecules, 2018
The preparation of 5-methylene-thiohydantoins using solid-phase synthesis is reported in this paper. After sulfonylation of immobilized Ser (t-Bu)-OH with 4-nitrobenzenesulfonyl chloride followed by alkylation with various bromoketones, the 4-Nos group ...
Petra Králová   +3 more
doaj   +1 more source

1-[N-Methyl-N-(Phenyl)amino]-3-(4-Methylphenyl)–Thiourea

open access: yesMolbank, 2019
The title compound, 1-[N-methyl-N-(phenyl)amino]-3-(4-methylphenyl)thiourea (1), was synthesized by the reaction of 1-methyl-1-phenyl hydrazine and 4-tolyl isothiocyanate, and was characterized by spectroscopy (1H and 13C{1H} NMR, IR, and UV), elemental ...
Chien Ing Yeo, Edward R. T. Tiekink
doaj   +1 more source

Home - About - Disclaimer - Privacy