Results 81 to 90 of about 52,767 (240)

Methyl 6,7-Difluoro-2-[(4-fluorobenzyl)sulfanyl]-4-hydroxyquinoline-3-carboxylate

Molbank
A convenient synthesis of a novel fluoroquinolone precursor, methyl 6,7-difluoro-2-[(4-fluorobenzyl)sulfanyl]-4-hydroxyquinoline-3-carboxylate, at a 78% yield starting from 3,4-difluorophenyl isothiocyanate was developed. The structure of the product was
Vladimir A. Potapov, Irina A. Novokshonova, Maxim V. Musalov, Svetlana V. Amosova, Oleg A. Rakitin   +4 more
doaj   +1 more source

Mesoporous Silica Nanoparticles‐Based Formulations for Enhanced Oral Delivery of Peptide Drugs: A Case Study on Insulin

Small, EarlyView.
This work explores the tailored functionalization of mesoporous silica nanoparticles (MSN) to improve the oral delivery of insulin, as a case study. Insulin confinement within silica mesopores increased drug solubility, and co‐formulation with succinylated β‐lactoglobulin yielded pH‐responsive tablets that limited gastric release and proteolysis, while
Claudia Iriarte‐Mesa, Estelle Juère, Andrea Bileck, Thomas Kremsmayr, Michael L. Goodson, Allison Ehrlich, Adnan Hodžić, Martin Kunert, Christopher Gerner, Hanspeter Kählig, Doris Marko, Markus Muttenthaler, David Berry, Giorgia Del Favero, Freddy Kleitz   +14 more
wiley   +1 more source

Synthesis of new 1, 8-dioxo-octahydroxanthene derivatives containing 4-thiazolidinone moiety containing 4-thiazolidinone moiety [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
A series of novel 1, 8-dioxo-octahydroxanthene derivatives containing 4-thiazolidinone framework (4a-f) were synthesized through a four-step reaction starting from the reduction of nitro derivatives of 1, 8-dioxo-octahydroxanthenes.
Maryam Robati, Dadkhoda Ghazanfari, Mohammad Reza Islami, Kazem Saidi   +3 more
doaj  

Evaluation of Microencapsulation of The UFV-AREG1 Bacteriophage in Alginate-Ca Microcapsules using Microfluidic Devices

, 2017
The indiscriminate use of antibiotics and the emergence of resistant microorganisms have become a major challenge for the food industry. The purpose of this work was to microencapsulate the bacteriophage UFV-AREG1 in a calcium alginate matrix using ...
Batalha, Laís S., Boggionea, Delaine M. G., Gontijo, Marco T. P., Lopez, Maryoris E. S., Mendonça, Regina C. S., Santos, Igor J. B., Teixeira, Alvaro V. N. C.   +6 more
core   +2 more sources

1-(4-Chlorophenyl)-3-(2,4-dichlorobenzoyl)thiourea [PDF]

, 2009
The title compound, C14H9Cl3N2OS, has bond lengths and angles which are quite typical for thiourea compounds of this class. The molecule exists in the solid state in its thione form with typical thiourea C=S and C=O bond lengths, as well as shortened C-N
M. Khawar Rauf, Michael Bolte, Amin Badshah, Allen, Baily, Blessing, Khawar Rauf, Khawar Rauf, Khawar Rauf, Khawar Rauf, Koch, Krishnamurthy, Maryanoff, Namgun, Patil, Sheldrick, Spek, Upadlgaya   +17 more
core   +1 more source

Macrophage Phenotype–Dependent Protein Corona Formation Governs Ligand Accessibility and Immune Clearance of Biomimetic Nanoparticles

Small, EarlyView.
Macrophage phenotype dictates protein corona composition and immune clearance of biomimetic nanoparticles. M0‐derived membranes minimize opsonin adsorption and complement activation, enabling superior immune evasion and prolonged circulation, thereby providing mechanistic insights for designing long‐circulating nanocarriers.
Tianchang He, Lina Zhu, Jiayi Ding, Xiaoyan Fang, Yu Gao, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +8 more
wiley   +1 more source

Effects of nematicides on nematode population densities and crop yield in a turnip-corn-pea cropping system [PDF]

, 1990
Nous avons évalué quatre systèmes de conduite de cultures lors d'une étude de 6 ans afin de lutter contre les nematodes dans un système annuel de production de navet-maïs-pois sur des parcelles de sable loameux Tifton naturellement infestées par les ...
Chalfant, R. B., Dowler, C.C., Epperson, J.E., Glaze, N. C., Golden, A.M., Johnson, A.W., Summer, D.R.   +6 more
core   +1 more source

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

The Chemical Record, EarlyView.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers

Molecules, 2018
Glucosinolates (GSL) are naturally occurring β-d-thioglucosides found across the cruciferous vegetables. Core structure formation and side-chain modifications lead to the synthesis of more than 200 types of GSLs in Brassicaceae.
Prabhakaran Soundararajan, Jung Sun Kim
doaj   +1 more source

Thia- and selenaheterocycles by a four-component reaction using elemental sulfur and selenium [PDF]

, 2006
The course of the four-component reactions of (2-benzimidazolyl) acetonitrile, carbondisulfide, isothiocyanate, and sulfur and selenium, respectively, is quite different.
Atanassov, P K, Heimgartner, H, Linden, Anthony   +2 more
core   +1 more source