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Analysis of Classical and Quantum Paths for Deprotonation of Methylamine by Methylamine Dehydrogenase

ChemPhysChem, 2007
AbstractThe hydrogen‐transfer reaction catalysed by methylamine dehydrogenase (MADH) with methylamine (MA) as substrate is a good model system for studies of proton tunnelling in enzyme reactions—an area of great current interest—for which atomistic simulations will be vital.
Ranaghan, Kara E.   +4 more
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The structure of liquid methylamine and solutions of lithium in methylamine

Molecular Physics, 2001
The technique of hydrogen/deuterium isotopic substitution in neutron diffraction has been used to measure the intra- and intermolecular correlations in liquid methylamine, and 2 and 8 MPM (mole percent metal) lithium methylamine solutions. We find that pure methylamine forms only one strong hydrogen bond per molecule, with evidence for weaker ...
S. HAYAMA   +3 more
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On methylamine assimilation in a bacterium

Archiv f�r Mikrobiologie, 1967
Kinetic analyses of 14C-methylamine and 14C-bicarbonate assimilation in a gram-negative diplococcus suggests that methylamine assimilation occurs via a glycine-serine hydroxymethylation sequence rather than autotrophically by a Calvin cycle.
E R, Leadbetter, J A, Gottlieb
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Methylamine in human urine

Clinica Chimica Acta, 2001
Methylamine is the simplest aliphatic amine found in human urine. In the body it is thought to play a significant part in central nervous system disturbances observed during renal and hepatic disease and also has a role in general toxicity caused by oxidative stress.
S C, Mitchell, A Q, Zhang
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Enzymology of Methylamine Dehydrogenase

1996
Methylamine dehydrogenase (MADH) belongs to the class of quinoprotein enzymes because it has tryptophyl tryptophanquinone (TTQ) as cofactor. In most cases, it is clear that the small blue copper protein, amicyanin, functions as natural electron acceptor.
Gorren, A.F.C.   +3 more
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The Photolysis of Methylamine

The Journal of Chemical Physics, 1944
The photolysis of methylamine has been shown to proceed essentially by two consecutive first-order reactions, the first to produce hydrogen, ammonia, and CH2 : NCH3; the second a dehydrogenation of the latter at a rate approximately double the first. A mechanism involving hydrogen atoms has been postulated.
Orville C. Wetmore, H. Austin Taylor
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