Results 131 to 140 of about 881,260 (340)

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans   +11 more
wiley   +1 more source

Pregnancy lipidomic profiles and DNA methylation in newborns from the CHAMACOS cohort. [PDF]

open access: yes, 2019
Lipids play a role in many biological functions and the newly emerging field of lipidomics aims to characterize the varying classes of lipid molecules present in biological specimens.
Bradman, Asa   +5 more
core  

Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer. [PDF]

open access: yes, 2016
Cytochrome P450 (CYP) 1A1 is a phase I enzyme that can activate various compounds into reactive forms and thus, may contribute to carcinogenesis. In this study, we investigated the expression, methylation status, and functional role of CYP1A1 on prostate
Chang, Inik   +15 more
core   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

open access: yesAdvanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig   +10 more
wiley   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

open access: yesAdvanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen   +13 more
wiley   +1 more source

Position Effect Takes Precedence Over Target Sequence in Determination of Adenine Methylation Patterns in the Nuclear Genome of a Eukaryote, \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]

open access: yes, 1998
Approximately 0.8% of the adenine residues in the macronuclear DNA of the ciliated protozoan Tetrahymena thermophila are modified to N6-methyladenine. DNA methylation is site specific and the pattern of methylation is constant between clonal cell lines ...
Karrer, Kathleen M.   +1 more
core   +1 more source

DNA methylation inhibits p53-mediated survivin repression [PDF]

open access: bronze, 2009
Nancy Nabilsi   +2 more
openalex   +1 more source

Differential DNA methylation and mRNA transcription in gingival tissues in periodontal health and disease

open access: green, 2021
Hyunjin Kim   +5 more
openalex   +2 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Sperm Mesoderm Specific Transcript Gene Methylation Status in Infertile Patients: A Systematic Review and Meta-Analysis

open access: yesThe World Journal of Men's Health
Purpose: The mesoderm specific transcription (MEST) gene is a paternally expressed imprinted gene that appears to play a role in embryo survival. The latest meta-analysis on MEST methylation pattern in spermatozoa of infertile patients found higher ...
Rossella Cannarella   +6 more
doaj   +1 more source

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