Results 141 to 150 of about 881,260 (340)
Advanced Materials Interfaces, EarlyView.Here, we reported a series of molecular‐rotor‐based photoactivated oxidase mimics, DAPy‐Xm, in which heavy atom incorporation enhances both ROS generation and cold‐adapted property. Among them, DAPy‐Im enables efficient photo‐oxidation of ergosterol and photocatalytic H2O2 production at low temperature.
Barbara Zenabu Anibea +3 more
wiley +1 more source
DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer [PDF]
, 2015 Kevin C. Johnson +8 more
openalex +1 more source
Bay‐functionalized [7]Helicene Bilayer Nanographenes
Advanced Optical Materials, EarlyView.Bay‐functionalized [7]helical bilayer nanographenes are synthesized via a scalable, modular strategy enabling late‐stage diversification. Tailored methoxy, diketone, and phenazine substitutions precisely tune redox, photophysical, and chiroptical properties, delivering strong electronic circular dichroism and bright circularly polarized luminescence ...
Anmol Thanai +9 more
wiley +1 more source
DNA methylation assessment from human slow- and fast-twitch skeletal muscle fibers [PDF]
, 2017 Gwénaëlle Begue +3 more
openalex +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Abundant Lysine Methylation and N-Terminal Acetylation in Sulfolobus islandicus Revealed by Bottom-Up and Top-Down Proteomics [PDF]
, 2016 Egor Vorontsov +4 more
openalex +1 more source
Advanced Science, EarlyView.Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source
Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
Advanced Science, EarlyView.This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang +51 more
wiley +1 more source
Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
Advanced Science, EarlyView.This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source