Results 231 to 240 of about 1,069,555 (390)

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

CRISPR-Cas9-induced double-strand breaks disrupt maintenance of epigenetic information. [PDF]

Genome Biol
Wang M, Zhang Y, Bi C, Li M.
europepmc   +1 more source

Analysis of DNA Methylation in Various Swine Tissues

, 2011
Chun Yang, Mingjun Zhang, Weiping Niu, Runjun Yang, Yonghong Zhang, Zhengyan Qiu, Boxing Sun, Zhihui Zhao   +7 more
openalex   +2 more sources

THE METHYL ESTER OF METHYLATED HYALURONIC ACID

Journal of Biological Chemistry, 1952
openaire   +2 more sources

Methyl Mercury [PDF]

Science, 1970
openaire   +2 more sources

METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression

Advanced Science, EarlyView.
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan, Huiwen Zhou, Jingsong Ma, Chensong Zhang, Yuhua Tan, Baoding Zhang, Jiabao Zhao, Ao Cheng, Chengyu Yang, Meijuan Xu, Shengyi Zhou, Yubo Xiong, Zeyang Lin, Guangchao Pan, Wenjie Ye, Mengya Zhong, Yang Yang, Yifan Zhuang, Shao‐Wei Li, Xianming Deng, Xuehui Hong   +20 more
wiley   +1 more source

Genome-wide demethylation and targeted remethylation during metamorphosis in the jewel wasp Nasonia vitripennis. [PDF]

Epigenetics Chromatin
Thomas CL, Mallon EB.
europepmc   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

Changes in nuclear and mitochondrial DNA methylation in cow blood associated with age and disease. [PDF]

Epigenetics
Bouzeraa L, de Lima CB, Martin H, Marques JCS, Cerri R, Oudihat M, Sirard MA.   +6 more
europepmc   +1 more source

The DNA methylation of FOXO3 and TP53 as a blood biomarker of late-onset asthma [PDF]

, 2020
Lin Yuan, Leyuan Wang, Xizi Du, Ling Qin, Ming Yang, Kai Zhou, Mengping Wu, Yu Yang, Zhiyuan Zheng, Yang Xiang, Xiangping Qu, Huijun Liu, Xiaoqun Qin, Chi Liu   +13 more
openalex   +1 more source