Results 231 to 240 of about 652,669 (356)

The methylation state of poly A-containing-messenger RNA from cultured hamster cells [PDF]

, 1975
Donald T. Dubin, Robert H. Taylor
openalex   +1 more source

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

Advanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao, Hui Zhang, Jingyi Wu, Yaqi Huang, Xiangnan Li, Meijia Wang, Shuming Wang, Jiaofeng Wang, Jie Chen, Zhi jun Bao, Li Jin, Xiaofeng Wang, Zixin Hu, Shuai Jiang, Yi Li   +14 more
wiley   +1 more source

Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors. [PDF]

Proc Natl Acad Sci U S A
Brennan RS, deMayo JA, Finiguerra M, Baumann H, Dam HG, Pespeni MH.   +5 more
europepmc   +1 more source

N"-Sulfonylformamidrazones, Methylation, Tosylation, Hydrolysis and Reaction with Amines. [PDF]

, 1978
Palle Jakobsen, Svend Treppendahl, Karen Thyssen   +2 more
openalex   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

DNA methylation in normal-appearing tissue associated with prostate cancer recurrence and metastasis. [PDF]

Clin Epigenetics
Pedersen CA, Fleischer T, Wess M, Midtbust E, Andersen MK, Viset T, Størkersen Ø, Rye MB, Tessem MB.   +8 more
europepmc   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

Detecting Methylation Changes Induced by Prime Editing. [PDF]

Genes (Basel)
Cosiquien RJS, Whalen IJ, Wong P, Sorensen RJ, Shetty AV, Liang SQ, Steer CJ.   +6 more
europepmc   +1 more source

Novel Methylation. VI. : N-Methylation of Primary Amines and Secondary Amines with Methyl Salicylate and Oxalate : Studies on the Syntheses of Heterocyclic Compounds. CCXXIII

, 1968
Tetsuji Kametani, KAZUO KIGASAWA, Tetsutaro Hayasaka   +2 more
openalex   +2 more sources

Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules

Advanced Science, EarlyView.
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu, Xinran Liu, Mei Xue, Yushuo Xiao, Yuchen Chen, Rong Qiu, Di Wu, Yihao Zhou, Jiao Wang, Yan Yuan, Linwei Yu, Tianyi Shi, Yangkai Li, Hua Su, Hong Chen, Yong Liu, Kun Huang, Ling Zheng   +17 more
wiley   +1 more source