Results 291 to 300 of about 1,050,423 (388)

T2T Genomes Unveil Centromere Architecture and Adaptive Divergence in Large Yellow Croaker (Larimichthys crocea)

Advanced Science, EarlyView.
This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui, Yingbo Yuan, Bi Wang, Baolan Wu, Mingyi Cai, Ming Fang, Weiliang Shen, Xiongfei Wu, Fang Han, Zhiyong Wang   +9 more
wiley   +1 more source

Long non-coding RNAs promote colorectal cancer development through other epigenetic modifications. [PDF]

Gastroenterol Rep (Oxf)
Wang G, Ma Q, Zhu N, Yan Y, Zhong C, Hong X, Lai Y, Chen X, Li N, Yu W.   +9 more
europepmc   +1 more source

PD‐L1‐Targeting Biomimetic Photoresponsive Thermosensitive Liposomes for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Tan et al. developed a platelet membrane‐coated, thermoresponsive liposome for targeted, light‐controlled delivery of fluorinated peptides that promotes programmed death‐ligand 1 degradation, induces tumor immunogenic cell death, suppresses solid tumors and metastases, and triggers durable immune memory, offering a promising strategy for peptide‐based ...
Manman Tan, Chengyu Shi, Guangyi Chi, Xinwan Su, Fangzhou Liu, Linyu Zhu, Guangqian Cheng, Xiangyi Chen, Meng Yu, Yijian Chen, Ying Wang, Yu Chen, ShuLing Yan, Wenfei Wu, Qingfeng Yan, Jianzhong Shao, Kai Wang, Xiangrui Liu, Min Zhou, Aifu Lin   +19 more
wiley   +1 more source

Multigenerational temperature effects on paternal epigenetic inheritance in European sea bass. [PDF]

Epigenetics Chromatin
Sánchez-Baizán N, Allal F, Vandeputte M, Piferrer F.   +3 more
europepmc   +1 more source

Novel Methylation. VI. : N-Methylation of Primary Amines and Secondary Amines with Methyl Salicylate and Oxalate : Studies on the Syntheses of Heterocyclic Compounds. CCXXIII

, 1968
Tetsuji Kametani, KAZUO KIGASAWA, Tetsutaro Hayasaka   +2 more
openalex   +2 more sources

Cell Fate Determination and Lineage Tracing: Technological Evolution and Multidimensional Applications

Advanced Science, EarlyView.
This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen, Zhicong Liu, Qiang Shu, Bin Zhou   +3 more
wiley   +1 more source

Epigenetic landscape of hormone-independent sexual dimorphism and characterization of canine XIST. [PDF]

Sci Rep
Oh SJ, Kang D, Jang S, Kim TS, Hong CY, Choe YH, Jo CH, You AS, Do YJ, Rho GJ, Kim J, Lee SL.   +11 more
europepmc   +1 more source

Dnmt1 Alleviates S1PR1‐Mediated Pyroptosis after Spinal Cord Injury through Regulating Pon3 Expression

Advanced Science, EarlyView.
This study systematically explores the action mechanism of Pon3 and its regulatory targets in spinal cord injury (SCI). It demonstrates that Dnmt1 regulates Pon3 expression by modulating methylation levels, thereby inhibiting S1PR1‐mediated pyroptosis and improving SCI prognosis.
Birong Peng, Haolong Lin, Mi Zhang, Wenhao Kuang, Jiaqi Zhang, Shuai Wang, Yuanfang Sun, Wenning Xu, Lixin Zhu   +8 more
wiley   +1 more source

Intermediate endophenotypes and epigenetic mechanisms of psychiatric disorders. [PDF]

Imaging Neurosci (Camb)
Kremer TL, Grimaldi DA, Fleischer H, Schwarz E, Meyer-Lindenberg A, Braun U, Tost H.   +6 more
europepmc   +1 more source

Enzymatic Methylation of Homocysteine by a Synthetic Tetrahydrofolate Derivative

, 1961
Warwick Sakami, I Ukstins
openalex   +1 more source