Results 321 to 330 of about 1,023,442 (398)

Tracing regulatory element networks using epigenetic traits to identify key transcription factors: TENET R/Bioconductor package. [PDF]

Bioinformatics
Mullen DJ, Wu Z, Nelson-Moore E, Cao H, Han L, Offringa IA, Rhie SK.   +6 more
europepmc   +1 more source

Integrating Molecular Dynamics and Machine Learning for Solvation‐Guided Electrolyte Optimization in Lithium Metal Batteries

Advanced Science, EarlyView.
A data‐driven workflow integrating molecular dynamics simulations and machine learning enables efficient discovery of optimized lithium battery electrolytes. Key structural descriptors are screened for predicting coordination behavior and ion transport. Gaussian process regression identifies an optimal feature space, guiding rational electrolyte design.
Xiwang Chang, Yang Yang, Weiheng Xu, Zhe Wang, Wenhan Li, Hongda Gao, Dubin Huang, Aijun Li, Yaofeng Zhu   +8 more
wiley   +1 more source

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

Advanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong, Hanwen Gu, Yuanqiang Zhang, Qunbo Meng, Qi Li, Kangle Song, Yanlin Li, Kaiwen Liu, Zhenchuan Liu, Rui Hu, Haoxi Zhai, Tian Li, Zemin Ling, Zhijian Wei, Fuxin Wei, Lei Cheng   +15 more
wiley   +1 more source

Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors. [PDF]

Proc Natl Acad Sci U S A
Brennan RS, deMayo JA, Finiguerra M, Baumann H, Dam HG, Pespeni MH.   +5 more
europepmc   +1 more source

Precise Modulation of Reorganization Energy through Methyl Substitution for High Performance Organic Solar Cells

Advanced Science, EarlyView.
This study reports the design of quinoxaline‐based electron acceptors with tailored methyl and halogen substitutions to modulate reorganization energy (λ) and enhance charge transport. we demonstrated that methylation effectively reduces λ, leading to minimized energy losses and improved device performance.
Li Chen, Chaoyue Zhao, Joshua Yuk Lin Lai, Rongkun Zhou, Aleksandr Sergeev, Kam Sing Wong, Huawei Hu, Zilong Zheng, Han Yu, Sai Ho Pun, Guangye Zhang, He Yan   +11 more
wiley   +1 more source

Detecting Methylation Changes Induced by Prime Editing. [PDF]

Genes (Basel)
Cosiquien RJS, Whalen IJ, Wong P, Sorensen RJ, Shetty AV, Liang SQ, Steer CJ.   +6 more
europepmc   +1 more source

DNA methylation in normal-appearing tissue associated with prostate cancer recurrence and metastasis. [PDF]

Clin Epigenetics
Pedersen CA, Fleischer T, Wess M, Midtbust E, Andersen MK, Viset T, Størkersen Ø, Rye MB, Tessem MB.   +8 more
europepmc   +1 more source

Transgenerational genetic and epigenetic changes induced by gamma-ray in Fagopyrum species. [PDF]

BMC Plant Biol
Sala-Cholewa K, Rojek-Jelonek M, Kwasniewska J.   +2 more
europepmc   +1 more source

IDH wild-type glioblastoma: Predictive value of standard-of-care (SOC) MRI for establishing MGMT promoter methylation status.

Neuroradiol J
Khalaj K, Tavakkol E, Nunez L, Jafarnia J, Dono A, Arevalo O, Rodriguez A, Zhu JJ, Esquenazi Y, Riascos R, Timaran-Montenegro D.   +10 more
europepmc   +1 more source