Results 41 to 50 of about 668 (126)

Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

, 2014
Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq.
Gruvberger, B., Johansen, J.D., Goncalo, M., Birgitta Gruvberger, Andersen, Klaus Ejner; id_orcid, Bruze, Magnus, Rustemeyer, T., Bruze, M., Bruze, Magnus,, White, Ian R, Isaksson, Marléne,, Andersen, K.E., Christophe‐J. Le Coz, Goossens, An, Goossens, A., Magnus Bruze, Isaksson, M., Rustemeyer, Thomas, Le Coz, Christophe-J., White, Ian R., Maibach, H.I., An Goossens, Gruvberger, Birgitta,, Gruvberger, Birgitta, Le Coz, Christophe-J, Thomas Rustemeyer, Howard I. Maibach, White, I.R., Johansen, Jeanne D., Le Coz, C.J., Marléne Isaksson, Klaus E. Andersen, Gonçalo, Margarida, Ian R. White, Maibach, Howard I, Margarida Gonçalo, Isaksson, Marléne, Andersen, Klaus E., Maibach, Howard I., Lund University., Jeanne D. Johansen, Andersen, Klaus E, Johansen, Jeanne D   +42 more
core   +1 more source

Mapping of Former Strategies and Future Needs for Regulatory Prevention of Skin Sensitization: Cosmetic Products

Contact Dermatitis, EarlyView.
This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen, Jakob Ferløv Baselius Schwensen, Jose Hernán Alfonso, Steen Mollerup, Gianluca Selvestrel, Christina Rudén, Martin F. Wilks, Jeanne Duus Johansen   +7 more
wiley   +1 more source

Concomitant contact allergies to formaldehyde, methylchloroisothiazolinone/methylisothiazolinone, methylisothiazolinone, and fragrance mixes I and II

, 2016
Background: Contact allergies to the preservatives formaldehyde and methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) have been reported to appear together at a statistically significant level.
Isaksson, Marléne, Dubnika Hauksson, Inese, Engfeldt, Malin, Bruze, Magnus, Pontén, Ann   +4 more
core   +1 more source

Occupational Allergic Contact Dermatitis From Over‐Ear Headphones: Chemical Analysis Reveals Octylisothiazolinone and Other Potential Skin Sensitizers

Contact Dermatitis, EarlyView.
ABSTRACT Background Over‐ear headphones are a growing source of allergic contact dermatitis (ACD). Identifying well‐known and new culprit sensitizers in such products is challenging because of a lack of labelling and limited cooperation from manufacturers.
Goël Fenech, Eddy Langlois, Eric Pelletier, Catherine Champmartin, Lynda Bensefa‐Colas, Marie‐Noëlle Crepy   +5 more
wiley   +1 more source

Targeted keratin repair: A plant‐based approach to hair strength and surface restoration

International Journal of Cosmetic Science, EarlyView.
Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge, Loya Schoeffel, Stefan Hettwer, Andreas Bosch, Cosimo Kropp, Brigit Suter, Barbara Obermayer   +6 more
wiley   +1 more source

European Society of Contact Dermatitis Guideline for Diagnostic Patch Testing—Recommendations on Best Practice (Update 2026)

Contact Dermatitis, Volume 95, Issue 3, Page 237-275, September 2026.
ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter, Olivier Aerts, Tove Agner, Richard Brans, Magnus Bruze, Alicia Cannavó, Marie‐Noёlle Crépy, Ana M. Giménez‐Arnau, Margarida Gonçalo, An Goossens, Swen M. John, Carola Lidén, Suzana Ljubojević Hadžavdić, Vera Mahler, Mihaly Matura, Esen Özkaya, Maria Pesonen, Nadia Raison‐Peyron, Thomas Rustemeyer, Radoslaw Spiewak, Luca Stingeni, Ian R. White, S. Mark Wilkinson, Jeanne Duus Johansen   +23 more
wiley   +1 more source

Contact Sensitization in Patients With Frontal Fibrosing Alopecia: Patch Test Results With an Extended Baseline Series in Consecutive Patients

Contact Dermatitis, Volume 95, Issue 2, Page 192-199, August 2026.
Sensitization to propolis, shellac and gallate mix is FFA‐associated, but its relevance is largely unknown. Sensitization to salicylates is frequent and associated with symptoms of intolerance to sun exposure or sunscreens. No significant improvement by allergen avoidance is identified.
María‐Antonia Pastor‐Nieto, María Elena Gatica Ortega, Anna María Giménez‐Arnau, Tatiana Sanz‐Sánchez, Pedro Mercader García, Inmaculada Ruíz‐González, Gemma Melé‐Ninot, Pablo Chicharro, Paloma Sánchez‐Pedreño, Marina de Vega, Miguel Ángel Gallego Descalzo, Leopoldo Borrego   +11 more
wiley   +1 more source

The Role of Cleaning Products in Epidemic Allergic Contact Dermatitis to Methylchloroisothiazolinone/Methylisothiazolinone

, 2018
Background Sensitivity to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) has increased rapidly over recent years. This increase is mainly related to the extensive use of high concentrations of MI in cosmetic products, although a growing ...
Gabriel Marrero-Alemán, Liuti, Federica, Pedro Saavedra Santana, Leopoldo Borrego, Noelia Hernández, López-Jiménez, Esmeralda, Saavedra Santana, Pedro, Hernández, Noelia, Federica Liuti, Esmeralda López-Jiménez, Borrego, Leopoldo, Marrero-Alemán, Gabriel   +11 more
core   +1 more source

Patch Testing With Methylchloroisothiazolinone/Methylisothiazolinone Using a New Diagnostic Mix-A Multicenter Study From the International Contact Dermatitis Research Group

, 2021
BACKGROUND: In the early 1980s, a preservative containing a mixture of methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) in a ratio of 3:1 was introduced. This mixture (mix) has been patch tested at 100 ppm (0.01%) worldwide and at 200 ppm
Melanie Pratt, Goncalo, Margarida, Puangpet, Pailin, Kaushal Verma, Andersen, Klaus E; id_orcid, Bruze, Magnus, Goh, Chee Leok, Goossens, An, Suzana Ljubojevic Hadzavdic, Magnus Bruze, Hadzavdic, Suzana Ljubojevic, Denis Sasseville, Elsner, Peter, Pailin Puangpet, Sasseville, Denis, Verma, Kaushal, An Goossens, Chee-Leok Goh, Goh, Chee-Leok, Marléne Isaksson, Pratt, Melanie, Klaus E. Andersen, Isaksson, Marlene, Margarida Gonçalo, Andersen, Klaus E., Peter Elsner   +25 more
core   +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, Volume 53, Issue 8, Page 1550-1561, August 2026.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source